Piperidine-3-carbaldehyde

Base Information

• Chemical Name: Piperidine-3-carbaldehyde
• CAS No.: 353290-29-6
• Molecular Formula: C₆H₁₁NO
• Molecular Weight: 113.159
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID20578751
• Mol file: 353290-29-6.mol

Synonyms:PIPERIDINE-3-CARBALDEHYDE;353290-29-6;3-Piperidinecarboxaldehyde;SCHEMBL519386;DTXSID20578751;AKOS006355486;SB41311;AM100710;D87810;EN300-6457670

Chemical Property of Piperidine-3-carbaldehyde

Chemical Property:

• Vapor Pressure: 0.864mmHg at 25°C
• Boiling Point: 181.168oC at 760 mmHg
• Flash Point: 80.848oC
• PSA: 29.10000
• Density: 1.038g/cm3
• LogP: 0.51370
• XLogP3: -0.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 113.084063974
• Heavy Atom Count: 8
• Complexity: 82.6

Purity/Quality:

98% ^*data from raw suppliers

Piperidine-3-carbaldehyde 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(CNC1)C=O

Technology Process of Piperidine-3-carbaldehyde

There total 1 articles about Piperidine-3-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ piperidine-3-carbaldehyde (353290-29-6)

Guidance literature:

With hydrogenchloride; das Hydrochlorid entsteht;

Reference yield:

piperidine-3-carbaldehyde (353290-29-6) + 4-(3,4-dichloro-phenoxy)-piperidine (245057-73-2) + Glyoxilic acid (298-12-4) + phenylboronic acid (98-80-6) → C25H30Cl2N2O3 (868056-91-1)

Guidance literature:

piperidine-3-carbaldehyde; 4-(3,4-dichloro-phenoxy)-piperidine; With sodium triacetoxy borohydride; acetic acid; In dichloromethane; at 20 ℃; for 18h;

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 16h;

Glyoxilic acid; phenylboronic acid; In ethanol; dichloromethane; at 100 ℃; Microwave irradiation;

DOI:10.1016/j.bmcl.2012.08.103

Reference yield:

piperidine-3-carbaldehyde (353290-29-6) + phenylacetonitrile (140-29-4) + tert–butyl (2–aminophenyl)carbamate (146651-75-4) + benzoic acid (65-85-0,8013-63-6) → C27H28N4O

Guidance literature:

piperidine-3-carbaldehyde; phenylacetonitrile; tert–butyl (2–aminophenyl)carbamate; benzoic acid; In methanol; at 20 ℃; for 36h;

With hydrogenchloride; In 1,4-dioxane; water;

DOI:10.1021/jm500632s

Downstream raw materials:

C₂₅H₃₀Cl₂N₂O₃

C₂₀H₂₃N₃O