2-Methoxy-2-methylpropanal

Base Information

• Chemical Name: 2-Methoxy-2-methylpropanal
• CAS No.: 36133-35-4
• Molecular Formula: C5H10O2
• Molecular Weight: 102.133
• European Community (EC) Number: 827-776-0
• DSSTox Substance ID: DTXSID70603744
• Nikkaji Number: J2.716.676H
• Wikidata: Q82501249
• Mol file: 36133-35-4.mol

Synonyms:2-methoxy-2-methylpropanal;36133-35-4;2-methoxy-2-methylpropionaldehyde;Propanal, 2-methoxy-2-methyl-;SCHEMBL1536745;DTXSID70603744;HSCUZOQCNBPBST-UHFFFAOYSA-N;2-methoxy-2-methyl propionaldehyde;AKOS040805716;DB-304708;DB-324012;3-methyl-1-trityl-1h-4-pyrazolylboronic acid;EN300-253710

Chemical Property of 2-Methoxy-2-methylpropanal

Chemical Property:

• XLogP3: 0.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 102.068079557
• Heavy Atom Count: 7
• Complexity: 66.5

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C=O)OC

Technology Process of 2-Methoxy-2-methylpropanal

There total 1 articles about 2-Methoxy-2-methylpropanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl methyl ether (1634-04-4) → tert-butyl formate (762-75-4) + acetone (67-64-1) + 2-methoxy-2-methylpropionaldehyde (36133-35-4) + tert-butyl alcohol (75-65-0)

Guidance literature:

With ozone; In water; at 12 ℃; pH=7; Further Variations:; Reagents; Kinetics;

DOI:10.1021/es010044n

Reference yield: 33.0%

2-((5-(2-(6-amino-2-methylhexan-3-yl)-2,6-diazaspiro[3.4]octan-6-yl)-1,2,4-triazin-6-yl)oxy)-N-ethyl-5-fluoro-N-isopropylbenzamide formate + 2-methoxy-2-methylpropionaldehyde (36133-35-4) → N-ethyl-5-fluoro-N-isopropyl-2-((5-(2-(6-((2-methoxy-2-methylpropyl)amino)-2-methylhexan-3-yl)-2,6-diazaspiro[3.4]octan-6-yl)-1,2,4-triazin-6-yl)oxy)benzamide

Guidance literature:

With methanol; sodium cyanoborohydride; at 20 ℃;

Reference yield: 28.0%

(R)-N-(1-(2-cyanoacetyl)piperidin-3-yl)-5-(2-methyl-4-phenoxyphenyl)-4-oxo-4,5-dihydro-3H-1-thia-3,5,8-triazaacenaphthylene-2-carboxamide + 2-methoxy-2-methylpropionaldehyde (36133-35-4) → (R,E)-N-(1-(2-cyano-4-methoxy-4-methylpent-2-enoyl)piperidin-3-yl)-5-(2-methyl-4-phenoxyphenyl)-4-oxo-4,5-dihydro-3H-1-thia-3,5,8-triazaacenaphthylene-2-carboxamide

Guidance literature:

With piperidine; In ethanol; at 20 ℃; for 1h; Inert atmosphere;

upstream raw materials:

tert-butyl methyl ether