Thiophen-2-ylmethanamine hydrochloride

Base Information

Chemical Name:Thiophen-2-ylmethanamine hydrochloride
CAS No.:7404-63-9
Molecular Formula:C5H7NS^.HCl
Molecular Weight:149.644
Hs Code.:2934999090
European Community (EC) Number:231-011-0
NSC Number:400116
DSSTox Substance ID:DTXSID10995458
Mol file:7404-63-9.mol

Synonyms:7404-63-9;thiophen-2-ylmethanamine hydrochloride;2-Thienylmethanamine;2-Thenylamine, hydrochloride;2-thenylamine hydrochloride;2-Thiophenemethylamine HCl;SCHEMBL11377269;DTXSID10995458;NSC400116;AKOS015947695;NSC-400116;1-(Thiophen-2-yl)methanamine--hydrogen chloride (1/1)

Suppliers and Price of Thiophen-2-ylmethanamine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
N-Methylthiophen-2-aminehydrochloride 95+%
1g
$ 314.00

Chemenu
N-methylthiophen-2-aminehydrochloride 95%
1g
$ 297.00

American Custom Chemicals Corporation
2-THIENYLMETHYLAMINE HYDROCHLORIDE 95.00%
5MG
$ 501.00

Alichem
N-Methylthiophen-2-aminehydrochloride
1g
$ 400.00

Total 15 raw suppliers

Chemical Property of Thiophen-2-ylmethanamine hydrochloride

Chemical Property:

Vapor Pressure:0.44mmHg at 25°C
Boiling Point:194.5 °C at 760 mmHg
Flash Point:73.9 °C
PSA：40.27000
LogP:2.66480
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:149.0065981
Heavy Atom Count:8
Complexity:56

Purity/Quality:

99%, ^*data from raw suppliers

N-Methylthiophen-2-aminehydrochloride 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CSC(=C1)CN.Cl

Technology Process of Thiophen-2-ylmethanamine hydrochloride

There total 11 articles about Thiophen-2-ylmethanamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 27757-85-3
2-Aminomethylthiophene

: 1849-02-1
2-chloro-1-methyl-benzimidazole

: 7404-63-9
thiophen-2-ylmethanamine monohydrochloride

: 343589-18-4
1-methyl-N-(thiophen-2-ylmethyl)-1H-benzo[d]imidazol-2-amine

Guidance literature:: In neat (no solvent); at 120 ℃; for 16h; Schlenk technique; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.joc.1c01467

Reference yield: 84.0%

: 124316-00-3
1-<<(Triphenylphosphoranylidene)amino>methyl>benzotriazole

: 5713-61-1
thiophen-2-yl magnesium bromide

: 7404-63-9
thiophen-2-ylmethanamine monohydrochloride

Guidance literature:: With hydrogenchloride; 1.) THF/diethyl ether, 20 min, rt.; 2.) diethyl ether, 1h;
DOI:10.1016/S0040-4039(00)99227-X

Reference yield: 74.0%

: 5813-89-8
2-thiophenylcarboxamide

: 7404-63-9
thiophen-2-ylmethanamine monohydrochloride

Guidance literature:: 2-thiophenylcarboxamide; With [(aNHC)KN(SiMe₃)₂]₂; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane; In toluene; at 40 ℃; for 12h; Inert atmosphere; Glovebox; Schlenk technique;

With water; sodium hydroxide; In diethyl ether; toluene; at 40 ℃; for 1h; Inert atmosphere; Glovebox; Schlenk technique;

With hydrogenchloride; In diethyl ether; water; Inert atmosphere; Glovebox; Schlenk technique;
DOI:10.1039/c9sc05953a