2-(3-Methoxyphenyl)-5-(trifluoromethyl)pyridine

Base Information

Chemical Name:2-(3-Methoxyphenyl)-5-(trifluoromethyl)pyridine
CAS No.:370878-65-2
Molecular Formula:C13H10F3NO
Molecular Weight:253.224
Hs Code.:2933399990
DSSTox Substance ID:DTXSID001241964
Nikkaji Number:J1.567.407E
Mol file:370878-65-2.mol

Synonyms:2-(3-Methoxyphenyl)-5-(trifluoromethyl)pyridine;SCHEMBL1416923;WNCPHYQOEBGTSR-UHFFFAOYSA-N;DTXSID001241964

Suppliers and Price of 2-(3-Methoxyphenyl)-5-(trifluoromethyl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Rieke Metals
2-(3-METHOXYPHENYL)PYRIDINE
5g
$ 1943.00

Rieke Metals
2-(3-METHOXYPHENYL)PYRIDINE
1g
$ 809.00

Matrix Scientific
2-(3-Methoxyphenyl)-pyridine 95%+
1g
$ 580.00

American Custom Chemicals Corporation
2-(3-METHOXYPHENYL)PYRIDINE 95.00%
5G
$ 867.12

Advanced Chemicals Intermediatesced Chemicals Intermediates
2-(3-Methoxy-phenyl)-pyridine 95%+
10g
$ 1732.75

Acints
2-(3-Methoxy-phenyl)-pyridine 95%+
10g
$ 1732.75

Acints
2-(3-Methoxy-phenyl)-pyridine 95%+
5g
$ 978.75

Acints
2-(3-Methoxy-phenyl)-pyridine 95%+
1g
$ 282.75

Total 6 raw suppliers

Chemical Property of 2-(3-Methoxyphenyl)-5-(trifluoromethyl)pyridine

Chemical Property:

PSA：22.12000
LogP:2.75720
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:253.07144843
Heavy Atom Count:18
Complexity:270

Purity/Quality:

99% ^*data from raw suppliers

2-(3-METHOXYPHENYL)PYRIDINE ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC(=C1)C2=NC=C(C=C2)C(F)(F)F

Technology Process of 2-(3-Methoxyphenyl)-5-(trifluoromethyl)pyridine

There total 4 articles about 2-(3-Methoxyphenyl)-5-(trifluoromethyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 10365-98-7,1107579-37-2
3-methoxyphenylboronic acid

: 52334-81-3
2-chloro-5-trifluoromethylpyridine

: 370878-65-2
2-(3-methoxyphenyl)-5-(trifluoromethyl)pyridine

Guidance literature:: With palladium diacetate; potassium carbonate; nixantphos; In tetrahydrofuran; water; at 20 ℃; for 6h;
DOI:10.1039/c5ra19790b

Reference yield: 73.0%

: 52334-81-3
2-chloro-5-trifluoromethylpyridine

: (3-methoxyphenyl)zinc(II) chloride

: 370878-65-2
2-(3-methoxyphenyl)-5-(trifluoromethyl)pyridine

Guidance literature:: With Li₂CoCl₄; sodium formate; In tetrahydrofuran; at 25 ℃; Inert atmosphere; Schlenk technique;
DOI:10.1002/anie.201510665