tert-butyl(dimethyl){[(1R,2S)-2-(prop-2-yn-1-yl)cyclohexyl]oxy}silane

Base Information

Chemical Name:tert-butyl(dimethyl){[(1R,2S)-2-(prop-2-yn-1-yl)cyclohexyl]oxy}silane
CAS No.:101859-17-0
Molecular Formula:C15H28 O Si
Molecular Weight:252.4677
Hs Code.:
Mol file:101859-17-0.mol

Synonyms:Silane,(1,1-dimethylethyl)dimethyl[[2-(2-propynyl)cyclohexyl]oxy]-, trans-

Suppliers and Price of tert-butyl(dimethyl){[(1R,2S)-2-(prop-2-yn-1-yl)cyclohexyl]oxy}silane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of tert-butyl(dimethyl){[(1R,2S)-2-(prop-2-yn-1-yl)cyclohexyl]oxy}silane

Chemical Property:

Vapor Pressure:0.00796mmHg at 25°C
Boiling Point:276.7°Cat760mmHg
Flash Point:118.4°C
Density:0.88g/cm³

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl(dimethyl){[(1R,2S)-2-(prop-2-yn-1-yl)cyclohexyl]oxy}silane

There total 1 articles about tert-butyl(dimethyl){[(1R,2S)-2-(prop-2-yn-1-yl)cyclohexyl]oxy}silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 101859-16-9
trans-2-(2-propynyl)-1-cyclohexanol

: 101859-17-0
(1R*,2S*)-1-((tert-butyldimethylsilyl)oxy)-2-(2-propynyl)cyclohexane

Guidance literature:: With dmap; TEA; In tetrahydrofuran; N,N-dimethyl-formamide; for 24h; Heating;
DOI:10.1021/jo00362a014

Reference yield:

: 101859-17-0
(1R*,2S*)-1-((tert-butyldimethylsilyl)oxy)-2-(2-propynyl)cyclohexane

: 101859-10-3
(1R*,2S*,(2E,5E))-2-(2-methyldodeca-2,5-dienyl)cyclohexan-1-ol

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) Cp₂ZrCl₂, 2.) iodine / 1.) CH₂Cl₂, toluene, 21 deg C, 6 h, 2.) CH₂Cl₂, toluene, THF, 0 deg C, 20 min.

3: 72 percent / (NH₄)2SO₄, tert-butyl alcohol, NH₃, Li / tetrahydrofuran

4: 88 percent / Et₃N, 1M tetra-n-butylammonium fluoride / tetrahydrofuran / 25 h / 21 °C

With ammonium sulfate; zirconocene dichloride; tetrabutyl ammonium fluoride; ammonia; iodine; lithium; triethylamine; tert-butyl alcohol; In tetrahydrofuran;
DOI:10.1021/jo00362a014

Reference yield:

: 101859-17-0
(1R*,2S*)-1-((tert-butyldimethylsilyl)oxy)-2-(2-propynyl)cyclohexane

: 101859-09-0
tert-Butyl-dimethyl-[(1R,2S)-2-((2E,5E)-2-methyl-dodeca-2,5-dienyl)-cyclohexyloxy]-silane

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) Cp₂ZrCl₂, 2.) iodine / 1.) CH₂Cl₂, toluene, 21 deg C, 6 h, 2.) CH₂Cl₂, toluene, THF, 0 deg C, 20 min.

3: 72 percent / (NH₄)2SO₄, tert-butyl alcohol, NH₃, Li / tetrahydrofuran

With ammonium sulfate; zirconocene dichloride; ammonia; iodine; lithium; tert-butyl alcohol; In tetrahydrofuran;
DOI:10.1021/jo00362a014