3-(2-Methoxy-phenyl)-2-phenyl-3H-quinazolin-4-one

Base Information

Chemical Name:3-(2-Methoxy-phenyl)-2-phenyl-3H-quinazolin-4-one
CAS No.:37856-18-1
Molecular Formula:C₂₁H₁₆N₂O₂
Molecular Weight:328.37
Hs Code.:
DSSTox Substance ID:DTXSID501238140
ChEMBL ID:CHEMBL1528387
Mol file:37856-18-1.mol

Synonyms:Oprea1_402662;MLS001205617;3-(2-Methoxy-phenyl)-2-phenyl-3H-quinazolin-4-one;CHEMBL1528387;DTXSID501238140;HMS2842P10;STK013649;AKOS000661186;SMR000517017;EU-0035630;SR-01000407679;3-(2-Methoxyphenyl)-2-phenyl-4(3H)-quinazolinone;3-(2-methoxyphenyl)-2-phenylquinazolin-4(3H)-one;SR-01000407679-1;37856-18-1

Suppliers and Price of 3-(2-Methoxy-phenyl)-2-phenyl-3H-quinazolin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(2-Methoxy-phenyl)-2-phenyl-3H-quinazolin-4-one

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:328.121177757
Heavy Atom Count:25
Complexity:512

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=CC=C1N2C(=NC3=CC=CC=C3C2=O)C4=CC=CC=C4

Technology Process of 3-(2-Methoxy-phenyl)-2-phenyl-3H-quinazolin-4-one

There total 7 articles about 3-(2-Methoxy-phenyl)-2-phenyl-3H-quinazolin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 611-73-4
Benzoylformic acid

: 70083-21-5
2-amino-N-(2-methoxyphenyl)benzamide

: 37856-18-1
3-(2-methoxyphenyl)-2-phenylquinazolin-4(3H)-one

Guidance literature:: With air; In water; at 110 ℃; for 14h; Green chemistry;
DOI:10.1021/acs.joc.1c01497

Reference yield:

: 5395-00-6
N-(2-methoxyphenyl)benzamide

: 37856-18-1
3-(2-methoxyphenyl)-2-phenylquinazolin-4(3H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: PCl₅

3: Na₂S₂O₄; aqueous ethanol

With sodium dithionite; ethanol; phosphorus pentachloride;
DOI:10.1093/gerona/56.12.B497