Benzyl-pyridin-4-ylmethyl-amine

Base Information

• Chemical Name: Benzyl-pyridin-4-ylmethyl-amine
• CAS No.: 73325-67-4
• Molecular Formula: C13H14N2
• Molecular Weight: 198.268
• Hs Code.: 2933399090
• Nikkaji Number: J830.500E
• Mol file: 73325-67-4.mol

Synonyms:Benzyl-pyridin-4-ylmethyl-amine;73325-67-4;Benzylpyridin-4-ylmethylamine;N-Benzyl-1-(pyridin-4-yl)methanamine;1-phenyl-N-(pyridin-4-ylmethyl)methanamine;n-benzyl-n-(pyridin-4-ylmethyl)amine;benzyl(4-pyridylmethyl)amine;benzyl(pyridin-4-ylmethyl)amine;4-pyridinemethanamine, n-(phenylmethyl)-;SCHEMBL1042566;N-benzyl(4-pyridyl) methylamine;benzyl[(pyridin-4-yl)methyl]amine;YCA32567;BBL029998;MFCD03425011;STK997025;AKOS000226315;SB54157;4-pyridinemethanamine, n-(phenylmethyl);AM804295;TS-00327;CS-0312739;FT-0641455

Chemical Property of Benzyl-pyridin-4-ylmethyl-amine

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.602
• Boiling Point: 330.4 °C at 760 mmHg
• Flash Point: 153.7 °C
• PSA: 24.92000
• Density: 1.071 g/cm³
• LogP: 2.76230
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 198.115698455
• Heavy Atom Count: 15
• Complexity: 158

Purity/Quality:

97% ^*data from raw suppliers

Benzyl-pyridin-4-ylmethyl-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CNCC2=CC=NC=C2

Technology Process of Benzyl-pyridin-4-ylmethyl-amine

There total 22 articles about Benzyl-pyridin-4-ylmethyl-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-pyridylmethyl(N-benzylamino)phenylphosphinic acid (653565-03-8) → 4-<(N-benzylamino)methyl>pyridine (73325-67-4)

Guidance literature:

With sulfuric acid; at 20 ℃; for 72h;

DOI:10.1081/SCC-120026350

Reference yield: 56.0%

C13H12N2 → 4-<(N-benzylamino)methyl>pyridine (73325-67-4)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 - 20 ℃; for 2h; Schlenk technique;

DOI:10.1002/adsc.201200944

Reference yield: 56.0%

4-(aminomethyl)pyridine (3731-53-1) + benzyl bromide (100-39-0) → 4-<(N-benzylamino)methyl>pyridine (73325-67-4)

Guidance literature:

In tetrahydrofuran; at 20 ℃;

DOI:10.1055/s-2007-990904

upstream raw materials:

4-(aminomethyl)pyridine

benzyl bromide

(Benzylamino-pyridin-4-yl-methyl)-phosphonic acid diethyl ester

(benzylamino-pyridin-4-yl-methyl)-phosphonic acid diphenyl ester

Downstream raw materials:

Re(C₅NH₄C₅NH₄)(CO)3(C₅NH₄CH₂NHCH₂C₆H₅)⁽¹⁺⁾*PF₆^(1-)=(Re(C₁₀N₂H₈)(CO)3(C₁₃N₂H₁₄))PF₆

N-(2-pyridylmethyl)-benzylamine oxalate

C₁₇H₁₈N₂O₃

C₃₁H₃₄ClN₇O