2-Morpholinemethanol, 4-(phenylmethyl)-, methanesulfonate (ester)

Base Information

• Chemical Name: 2-Morpholinemethanol, 4-(phenylmethyl)-, methanesulfonate (ester)
• CAS No.: 385814-36-8
• Molecular Formula: C13H19NO4S
• Molecular Weight: 285.364
• Mol file: 385814-36-8.mol

Synonyms:2-Morpholinemethanol, 4-(phenylmethyl)-, methanesulfonate (ester)

Chemical Property of 2-Morpholinemethanol, 4-(phenylmethyl)-, methanesulfonate (ester)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Morpholinemethanol, 4-(phenylmethyl)-, methanesulfonate (ester)

There total 1 articles about 2-Morpholinemethanol, 4-(phenylmethyl)-, methanesulfonate (ester) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

R,S-2-hydroxymethyl-4-benzylmorpholine (40987-24-4,943442-96-4) + methanesulfonyl chloride (124-63-0) → 4-(phenylmethyl)-2-morpholinemethanol methanesulfonate (385814-36-8)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃; for 0.5h;

Reference yield: 75.0%

4-(phenylmethyl)-2-morpholinemethanol methanesulfonate (385814-36-8) → 2-(azidomethyl)-4-benzylmorpholine (112913-97-0)

Guidance literature:

With sodium azide; In DMF (N,N-dimethyl-formamide); at 80 ℃;

Reference yield:

4-(phenylmethyl)-2-morpholinemethanol methanesulfonate (385814-36-8) + N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-6-quinoxalinamine (1346133-39-8) → C32H34N6O3 (1346243-00-2)

Guidance literature:

N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxaline-6-amine; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 5 ℃; for 0.5h;

4-(phenylmethyl)-2-morpholinemethanol methanesulfonate; In N,N-dimethyl-formamide; mineral oil; at 60 ℃; for 18h;

upstream raw materials:

R,S-2-hydroxymethyl-4-benzylmorpholine

methanesulfonyl chloride

Downstream raw materials:

2-(azidomethyl)-4-benzylmorpholine

C₃₂H₃₄N₆O₃