Technology Process of N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-6-quinoxalinamine
There total 17 articles about N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-6-quinoxalinamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium t-butanolate;
palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl;
In
1,4-dioxane;
at 90 ℃;
Product distribution / selectivity;
Inert atmosphere;
- Guidance literature:
-
With
sodium t-butanolate;
palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl;
In
1,2-dimethoxyethane;
at 135 ℃;
for 1h;
Product distribution / selectivity;
Inert atmosphere;
microwave irradiation;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium carbonate / triphenylphosphine; palladium diacetate / 1,2-dimethoxyethane; water / 4 h / Reflux
2: sodium t-butanolate / palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / 1,4-dioxane / 90 °C / Inert atmosphere
With
sodium carbonate; sodium t-butanolate;
palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; triphenylphosphine;
In
1,4-dioxane; 1,2-dimethoxyethane; water;
