3-Chloro-3-(4-nitrophenyl)-3H-diazirine

Base Information

• Chemical Name: 3-Chloro-3-(4-nitrophenyl)-3H-diazirine
• CAS No.: 39184-67-3
• Molecular Formula: C7H4ClN3O2
• Molecular Weight: 197.581
• Mol file: 39184-67-3.mol

Synonyms:3-chloro-3-p-nitrophenyldiaziridine;(4-nitrophenyl)chlorodiazirine;chloro(p-nitrophenyl)diazirine;3-chloro-3-p-nitrophenyldiazirine;3-(p-nitrophenyl)-3-chlorodiazirine;3-chloro-3-(p-nitrophenyl)diazirine;

Chemical Property of 3-Chloro-3-(4-nitrophenyl)-3H-diazirine

Chemical Property:

• PSA: 70.54000
• Density: 1.67±0.1 g/cm3 (20 oC 760 Torr)
• LogP: 1.80410

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Chloro-3-(4-nitrophenyl)-3H-diazirine

There total 2 articles about 3-Chloro-3-(4-nitrophenyl)-3H-diazirine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.0%

4-nitrobenzamidine hydrochloride (15723-90-7) → 3-chloro-3-(p-nitrophenyl)diazirine (39184-67-3)

Guidance literature:

With sodium hypochlorite; lithium chloride; sodium chloride; In dimethyl sulfoxide; pentane; at 0 ℃;

DOI:10.1021/jacs.1c06287

Reference yield:

→ 3-chloro-3-(p-nitrophenyl)diazirine (39184-67-3)

Guidance literature:

entspr. Amidinhydrochlorid, NaClO;

DOI:10.1139/v72-479

Reference yield: 93.0%

ethoxyethoxyethanol (111-90-0) + 3-chloro-3-(p-nitrophenyl)diazirine (39184-67-3) → 2-chloroethyl ethyl ether (628-34-2) + 2-(4-nitrophenyl)-1,3-dioxolane (2403-53-4) + 1-dichloromethyl-4-nitrobenzene (619-78-3)

Guidance literature:

at 80 ℃; for 6h;

upstream raw materials:

4-nitrobenzamidine hydrochloride

Downstream raw materials:

3-(4-Nitro-phenyl)-indolizine-1-carbonitrile

4-nitrophenylchloropyridinium ylide

(1S,3aS,6aR)-1-Hydroxy-3,3,5-trimethyl-1-(4-nitro-phenyl)-tetrahydro-furo[3,4-c]pyrrole-4,6-dione

2-hydroxy-5,5-dimethyl-2-(p-nitrophenyl)-tetrahydrofuran-N-methyl-3,4-dicarboximide