2-AMINO-5-FLUOROBENZOIC ACID ETHYL ESTER

Base Information

• Chemical Name: 2-AMINO-5-FLUOROBENZOIC ACID ETHYL ESTER
• CAS No.: 391-93-5
• Molecular Formula: C9H10FNO2
• Molecular Weight: 183.182
• Hs Code.: 2922499990
• Mol file: 391-93-5.mol

Synonyms:2-Carboaethoxy-4-fluoranilin;2-Carboethoxy-4-fluoroaniline;2-Amino-5-fluor-benzoesaeure-aethylester;ethyl 5-fluoroanthranilate;2-amino-5-fluoro-benzoic acid ethyl ester;

Chemical Property of 2-AMINO-5-FLUOROBENZOIC ACID ETHYL ESTER

Chemical Property:

• PSA: 52.32000
• LogP: 2.16580
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

97% ^*data from raw suppliers

Ethyl2-amino-5-fluorobenzoate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-AMINO-5-FLUOROBENZOIC ACID ETHYL ESTER

There total 6 articles about 2-AMINO-5-FLUOROBENZOIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.9%

→ ethyl 2-amino-5-fluorobenzoate (391-93-5)

Guidance literature:

Reference yield: 50.0%

2-amino-5-fluorobenzoic acid (446-08-2) → ethyl 2-amino-5-fluorobenzoate (391-93-5)

Guidance literature:

With sulfuric acid; In ethanol; toluene;

Reference yield:

ethyl 5-fluoro-2-nitrobenzoate (364-51-2) → ethyl 2-amino-5-fluorobenzoate (391-93-5)

Guidance literature:

With ethanol; platinum; Hydrogenation;

DOI:10.1021/ja01235a032

upstream raw materials:

ethyl 5-fluoro-2-nitrobenzoate

5-fluoro-2-nitrobenzoic acid

5-fluoro-2-nitrobenzoyl chloride

2-amino-5-fluorobenzoic acid

Downstream raw materials:

ethyl 5-fluoro-3-hydroxyindole-2-carboxylate

3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione

C₈H₅FN₂O

2-chloro-6-fluoroquinazoline

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