2,2,2-trifluoro-N-(6-oxo-6-phenylhexyl)acetamide

Base Information

Chemical Name:2,2,2-trifluoro-N-(6-oxo-6-phenylhexyl)acetamide
CAS No.:39510-50-4
Molecular Formula:C₁₂H₁₇NO
Molecular Weight:191.273
Hs Code.:
Mol file:39510-50-4.mol

Synonyms:2,2,2-TRIFLUORO-1-(4-METHOXYPHENYL)ETHANAMINE HYDROCHLORIDE;6-amino-1-phenyl-hexan-1-one;2,2,2-tris(fluoranyl)-N-(6-oxidanylidene-6-phenyl-hexyl)ethanamide;1-Amino-6-oxo-6-phenyl-hexan;

Suppliers and Price of 2,2,2-trifluoro-N-(6-oxo-6-phenylhexyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2,2,2-trifluoro-N-(6-oxo-6-phenylhexyl)acetamide

Chemical Property:

PSA：46.17000
LogP:3.49910

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2,2,2-trifluoro-N-(6-oxo-6-phenylhexyl)acetamide

There total 9 articles about 2,2,2-trifluoro-N-(6-oxo-6-phenylhexyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 3466-83-9
2-phenylazepane hydrochloride

: 3338-00-9
2-phenyl-4,5,6,7-tetrahydro-3H-azepine

: 39510-50-4
6-amino-1-phenylhexan-1-one

: (R)-2-phenylazacycloheptane

Guidance literature:: With borane-ammonia complex; In aq. phosphate buffer; at 37 ℃; for 24h; pH=7.8; Reagent/catalyst; enantioselective reaction; Enzymatic reaction;
DOI:10.1021/jacs.8b11891

Reference yield:

: 3338-00-9
2-phenyl-4,5,6,7-tetrahydro-3H-azepine

: 39510-50-4
6-amino-1-phenylhexan-1-one

Guidance literature:: With water; In aq. phosphate buffer; at 20 ℃; pH=11; pH-value; Solvent;
DOI:10.1021/jacs.8b11891

Reference yield:

: 128372-99-6
(6-oxo-6-phenyl-hexyl)-carbamic acid tert-butyl ester

: 3338-00-9
2-phenyl-4,5,6,7-tetrahydro-3H-azepine

: 39510-50-4
6-amino-1-phenylhexan-1-one

Guidance literature:: (6-oxo-6-phenyl-hexyl)-carbamic acid tert-butyl ester; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 5h; Inert atmosphere;

With water; potassium hydroxide; In dichloromethane; at 0 ℃; pH=< 11;

With magnesium sulfate; In dichloromethane; at 20 ℃; Overall yield = 100 %; Overall yield = 5.13 g;
DOI:10.1021/jacs.8b11891