2-phenylazepane (HCl)

Base Information

Chemical Name:2-phenylazepane (HCl)
CAS No.:3466-83-9
Molecular Formula:C₁₂H₁₇N*ClH
Molecular Weight:211.735
Hs Code.:
Mol file:3466-83-9.mol

Synonyms:1H-Azepine,hexahydro-2-phenyl-, hydrochloride (9CI); Hexamethylenimine, 2-phenyl-,hydrochloride (7CI)

Suppliers and Price of 2-phenylazepane (HCl)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Phenylazepanehydrochloride 95+%
5g
$ 671.00

Chemenu
2-phenylazepanehydrochloride 95%
5g
$ 634.00

Alichem
2-Phenylazepanehydrochloride
1g
$ 400.00

Total 5 raw suppliers

Chemical Property of 2-phenylazepane (HCl)

Chemical Property:

PSA：12.03000
LogP:4.02210
Storage Temp.:Inert atmosphere,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

2-Phenylazepanehydrochloride 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-phenylazepane (HCl)

There total 6 articles about 2-phenylazepane (HCl) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3466-82-8
2-phenylazacycloheptane

: 3466-83-9
2-phenylazepane hydrochloride

Guidance literature:: With hydrogenchloride; In diethyl ether; at 0 ℃; for 0.5h; Inert atmosphere;
DOI:10.1021/jacs.8b11891

Reference yield:

: 105-60-2,9012-16-2
caprolactam

: 3466-83-9
2-phenylazepane hydrochloride

Guidance literature:: Multi-step reaction with 5 steps

1.1: dmap / acetonitrile / 20 °C / Inert atmosphere

2.1: tetrahydrofuran / -78 - 20 °C / Inert atmosphere

3.1: trifluoroacetic acid / dichloromethane / 5 h / 20 °C / Inert atmosphere

3.2: 0 °C / pH < 11

3.3: 20 °C

4.1: sodium tris(acetoxy)borohydride; acetic acid / dichloromethane / 20 °C / Molecular sieve; Inert atmosphere

5.1: hydrogenchloride / diethyl ether / 0.5 h / 0 °C / Inert atmosphere

With hydrogenchloride; dmap; sodium tris(acetoxy)borohydride; acetic acid; trifluoroacetic acid; In tetrahydrofuran; diethyl ether; dichloromethane; acetonitrile;
DOI:10.1021/jacs.8b11891

Reference yield:

: 106412-36-6
tert-butyl 2-oxoazepane-1-carboxylate

: 3466-83-9
2-phenylazepane hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1.1: tetrahydrofuran / -78 - 20 °C / Inert atmosphere

2.1: trifluoroacetic acid / dichloromethane / 5 h / 20 °C / Inert atmosphere

2.2: 0 °C / pH < 11

2.3: 20 °C

3.1: sodium tris(acetoxy)borohydride; acetic acid / dichloromethane / 20 °C / Molecular sieve; Inert atmosphere

4.1: hydrogenchloride / diethyl ether / 0.5 h / 0 °C / Inert atmosphere

With hydrogenchloride; sodium tris(acetoxy)borohydride; acetic acid; trifluoroacetic acid; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1021/jacs.8b11891