6,8-Dimethoxy-3-methyl-3,4-dihydroisocoumarin

Base Information

Chemical Name:6,8-Dimethoxy-3-methyl-3,4-dihydroisocoumarin
CAS No.:77844-97-4
Molecular Formula:C12H14 O4
Molecular Weight:222.241
Hs Code.:2932209090
DSSTox Substance ID:DTXSID30999054
Nikkaji Number:J2.538.645K
Mol file:77844-97-4.mol

Synonyms:6,8-dimethoxy-3-methyl-3,4-dihydroisocoumarin;6,8-DMD-isocoumarin

Suppliers and Price of 6,8-Dimethoxy-3-methyl-3,4-dihydroisocoumarin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 6,8-Dimethoxy-3-methyl-3,4-dihydroisocoumarin

Chemical Property:

Vapor Pressure:6.67E-07mmHg at 25°C
Boiling Point:409.1°C at 760 mmHg
Flash Point:185°C
PSA：44.76000
Density:1.158g/cm³
LogP:1.80520
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:222.08920892
Heavy Atom Count:16
Complexity:266

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC2=C(C(=CC(=C2)OC)OC)C(=O)O1

Technology Process of 6,8-Dimethoxy-3-methyl-3,4-dihydroisocoumarin

There total 1 articles about 6,8-Dimethoxy-3-methyl-3,4-dihydroisocoumarin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2524-37-0
ethyl orselinate

: 77844-97-4
3,4-dihydro-6,8-dimethoxy-3-methyl-1H-2-benzopyran-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / K₂CO₃ / acetone / Heating

2: 1.) LDA, 2.) acetaldehyde / 1.) THF, hexane-78 deg C, 30 min, 2.) THF, hexane, a.) -78deg C, 1 h, b.) RT, overnight

With potassium carbonate; acetaldehyde; lithium diisopropyl amide; In acetone;
DOI:10.1080/00397919208021540