2,2'-DITHIODIPROPIONIC ACID

Base Information

• Chemical Name: 2,2'-DITHIODIPROPIONIC ACID
• CAS No.: 4775-93-3
• Molecular Formula: C6H10O4S2
• Molecular Weight: 210.275
• Hs Code.: 2930909090
• Mol file: 4775-93-3.mol

Synonyms:2,2'-DITHIODIPROPIONIC ACID;

Chemical Property of 2,2'-DITHIODIPROPIONIC ACID

Chemical Property:

• Vapor Pressure: 6.64E-07mmHg at 25°C
• Melting Point: 117.5 °C
• Refractive Index: 1.4950 (estimate)
• Boiling Point: 431.1°Cat760mmHg
• PKA: 3.14±0.10(Predicted)
• Flash Point: 214.5°C
• PSA: 125.20000
• Density: 1.452g/cm³
• LogP: 1.31400

Purity/Quality:

99%, ^*data from raw suppliers

2,2'-Dithiodipropionic Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2'-DITHIODIPROPIONIC ACID

There total 33 articles about 2,2'-DITHIODIPROPIONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2-mercaptopropanoic acid (79-42-5) → 2,2'-dithiobispropanoic acid (4775-93-3)

Guidance literature:

With iodine; In water; at 100 ℃; for 0.5h; Microwave irradiation; Inert atmosphere;

DOI:10.1021/jm2001663

Reference yield: 59.0%

2-Bromopropionic acid (598-72-1,10327-08-9) → 2,2'-dithiobispropanoic acid (4775-93-3)

Guidance literature:

2-Bromopropionic acid; With sodium carbonate; sodium thiosulfate; In water; at 100 ℃; for 2h;

With iodine; In water; at 100 ℃; for 2h;

DOI:10.1021/ol063062o

Reference yield:

3-[(2S,3S)-1-hydroxy-2,4-dimethylpentan-3-yl]-5-methyl-thiazolidine-2,4-dione (1206518-31-1) → 2,2'-dithiobispropanoic acid (4775-93-3) + (4S,5S)-4-isopropyl-5-methyltetrahydro-2H-1,3-oxazin-2-one (1206518-39-9)

Guidance literature:

With water; potassium hydroxide; In tetrahydrofuran; at 20 ℃; for 4h;

DOI:10.1016/j.tet.2009.11.035

upstream raw materials:

2-mercaptopropanoic acid

iodine

iron(III) chloride

water

Downstream raw materials:

2-sulfopropionic acid

2-mercaptopropanoic acid

2-methyl-3-thiapentanoic acid

2,2'-disulfanediyl-bis-propionyl chloride