Pyridine, 2-bromo-6-(phenoxymethyl)-

Base Information

Chemical Name:Pyridine, 2-bromo-6-(phenoxymethyl)-
CAS No.:399031-16-4
Molecular Formula:C12H10BrNO
Molecular Weight:264.11800
Hs Code.:
DSSTox Substance ID:DTXSID50477400
Nikkaji Number:J1.657.542I
Wikidata:Q82309908
Mol file:399031-16-4.mol

Synonyms:399031-16-4;Pyridine, 2-bromo-6-(phenoxymethyl)-;DTXSID50477400

Suppliers and Price of Pyridine, 2-bromo-6-(phenoxymethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Pyridine, 2-bromo-6-(phenoxymethyl)-

Chemical Property:

PSA：22.12000
LogP:3.42310
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:262.99458
Heavy Atom Count:15
Complexity:183

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)OCC2=NC(=CC=C2)Br

Technology Process of Pyridine, 2-bromo-6-(phenoxymethyl)-

There total 4 articles about Pyridine, 2-bromo-6-(phenoxymethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 496840-11-0
2-bromo-6-(iodomethyl)pyridine

: 108-95-2,27073-41-2
phenol

: 399031-16-4
2-bromo-6-(phenoxymethyl)pyridine

Guidance literature:: With sodium hydride; In tetrahydrofuran; at 20 ℃; for 2h;
DOI:10.1246/bcsj.76.789

Reference yield: 93.0%

: 139-02-6
sodium phenoxide

: 496840-11-0
2-bromo-6-(iodomethyl)pyridine

: 399031-16-4
2-bromo-6-(phenoxymethyl)pyridine

Guidance literature:: In tetrahydrofuran; at 0 ℃;
DOI:10.1246/cl.2001.1230

Reference yield:

: 33674-96-3
2-bromo-6-(hydroxymethyl)pyridine

: 399031-16-4
2-bromo-6-(phenoxymethyl)pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / Et₃N; 4-(dimethylamino)pyridine / tetrahydrofuran / 2.5 h / -40 °C

2: 98 percent / NaI / acetone / 5.5 h / Heating

3: 93 percent / NaH / tetrahydrofuran / 2 h / 20 °C

With dmap; sodium hydride; triethylamine; sodium iodide; In tetrahydrofuran; acetone;
DOI:10.1246/bcsj.76.789