1H-Pyrazolo[4,3-c]pyridine, 5-acetyl-4,5,6,7-tetrahydro-1-[3-[4-(2-methylphenyl)-1-piperazinyl]-2-oxo propyl]-3-[4-(trifluoromethyl)phenyl]-

Base Information

Chemical Name:1H-Pyrazolo[4,3-c]pyridine, 5-acetyl-4,5,6,7-tetrahydro-1-[3-[4-(2-methylphenyl)-1-piperazinyl]-2-oxo propyl]-3-[4-(trifluoromethyl)phenyl]-
CAS No.:400802-93-9
Molecular Formula:C29H32F3N5O2
Molecular Weight:539.601
Hs Code.:

1H-Pyrazolo[4,3-c]pyridine,
5-acetyl-4,5,6,7-tetrahydro-1-[3-[4-(2-methylphenyl)-1-piperazinyl]-2-oxo
propyl]-3-[4-(trifluoromethyl)phenyl]-

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1H-Pyrazolo[4,3-c]pyridine, 5-acetyl-4,5,6,7-tetrahydro-1-[3-[4-(2-methylphenyl)-1-piperazinyl]-2-oxo propyl]-3-[4-(trifluoromethyl)phenyl]-

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Technology Process of 1H-Pyrazolo[4,3-c]pyridine, 5-acetyl-4,5,6,7-tetrahydro-1-[3-[4-(2-methylphenyl)-1-piperazinyl]-2-oxo propyl]-3-[4-(trifluoromethyl)phenyl]-

There total 3 articles about 1H-Pyrazolo[4,3-c]pyridine, 5-acetyl-4,5,6,7-tetrahydro-1-[3-[4-(2-methylphenyl)-1-piperazinyl]-2-oxo propyl]-3-[4-(trifluoromethyl)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 79-37-8
oxalyl dichloride

: 400802-46-2
1-[1-[2-hydroxy-3-(4-o-tolyl-piperazin-1-yl)-propyl]-3-(4-trifluoromethyl-phenyl)-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-5-yl]-ethanone

: 400802-93-9
1-[5-acetyl-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl]-3-(4-o-tolyl-piperazin-1-yl)-propan-2-one

Guidance literature:: With sodium hydrogencarbonate; triethylamine; In dichloromethane; dimethyl sulfoxide;

Reference yield:

: 400797-70-8
1-[1-oxiranylmethyl-3-(4-trifluoromethyl-phenyl)-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-5-yl]-ethanone

: 400802-93-9
1-[5-acetyl-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl]-3-(4-o-tolyl-piperazin-1-yl)-propan-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: dichloromethane

2: sodium hydrogencarbonate; triethylamine / dichloromethane; dimethyl sulfoxide

With sodium hydrogencarbonate; triethylamine; In dichloromethane; dimethyl sulfoxide;

Reference yield:

: 400797-69-5
1-[3-(4-trifluoromethyl-phenyl)-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-5-yl]-ethanone

: 400802-93-9
1-[5-acetyl-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl]-3-(4-o-tolyl-piperazin-1-yl)-propan-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: caesium carbonate / N,N-dimethyl-formamide

2: dichloromethane

3: sodium hydrogencarbonate; triethylamine / dichloromethane; dimethyl sulfoxide

With sodium hydrogencarbonate; caesium carbonate; triethylamine; In dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;