2-Pyridinecarboxylicacid,1,6-dihydro-5-methyl-6-oxo-,methylester(9CI)

Base Information

Chemical Name:2-Pyridinecarboxylicacid,1,6-dihydro-5-methyl-6-oxo-,methylester(9CI)
CAS No.:401792-80-1
Molecular Formula:C8H9NO3
Molecular Weight:167.164
Hs Code.:2933399090
Mol file:401792-80-1.mol

Synonyms:6-Hydroxy-5-methyl-pyridine-2-carboxylic acid methyl ester;methyl 6-hydroxy-5-methyl-2-pyridinecarboxylate;

Suppliers and Price of 2-Pyridinecarboxylicacid,1,6-dihydro-5-methyl-6-oxo-,methylester(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
methyl6-hydroxy-5-methylpicolinate 95%
1g
$ 421.00

Chemenu
methyl6-hydroxy-5-methylpicolinate 95%
25g
$ 2338.00

Chemenu
methyl6-hydroxy-5-methylpicolinate 95%
5g
$ 935.00

American Custom Chemicals Corporation
6-HYDROXY-5-METHYL-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER 95.00%
5MG
$ 498.49

Alichem
Methyl6-hydroxy-5-methylpicolinate
1g
$ 2837.10

Alichem
Methyl6-hydroxy-5-methylpicolinate
250mg
$ 1009.40

Total 3 raw suppliers

Chemical Property of 2-Pyridinecarboxylicacid,1,6-dihydro-5-methyl-6-oxo-,methylester(9CI)

Chemical Property:

PSA：59.42000
LogP:0.88220
Storage Temp.:2-8°C

Purity/Quality:

95+% ^*data from raw suppliers

methyl6-hydroxy-5-methylpicolinate 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Pyridinecarboxylicacid,1,6-dihydro-5-methyl-6-oxo-,methylester(9CI)

There total 5 articles about 2-Pyridinecarboxylicacid,1,6-dihydro-5-methyl-6-oxo-,methylester(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 1006364-86-8
methyl 1-benzyloxy-5-methyl-6-oxo-1,2,3,6-tetrahydropyridine-2-carboxylate

: 401792-80-1
methyl 5-methyl-6-oxo-1,6-dihydropyridine-2-carboxylate

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at 20 ℃;
DOI:10.1021/ol702684d

Reference yield: 60.0%

: 401792-77-6
methyl 5-methyl-2-pyridinecarboxylate N-oxide

: 401792-80-1
methyl 6-hydroxy-5-methyl-2-pyridinecarboxylate

Guidance literature:: methyl 5-methyl-2-pyridinecarboxylate N-oxide; With acetic anhydride; for 3h; Heating;

With sodium methylate; In methanol; at 0 ℃; for 0.166667h;
DOI:10.1016/S0957-4166(01)00414-1

Reference yield:

: 29681-38-7
methyl 5-methylpyridine-2-carboxylate

: 401792-80-1
methyl 6-hydroxy-5-methyl-2-pyridinecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: 78 percent / m-CPBA / CHCl₃ / 15 h / 20 °C

2.1: Ac₂O / 3 h / Heating

2.2: 51 percent / NaOMe / methanol / 0.17 h / 0 °C

With acetic anhydride; 3-chloro-benzenecarboperoxoic acid; In chloroform;
DOI:10.1016/S0040-4020(02)00670-1