2-Pyridinecarboxylic acid, 5-formyl-6-methoxy-, methyl ester

Base Information

Chemical Name:2-Pyridinecarboxylic acid, 5-formyl-6-methoxy-, methyl ester
CAS No.:401792-87-8
Molecular Formula:C9H9NO4
Molecular Weight:195.175
Hs Code.:
Mol file:401792-87-8.mol

Synonyms:methyl 5-formyl-6-methoxypicolinate;METHYL 5-FORMYL-6-METHOXY-2-PYRIDINECARBOXYLATE;5-FORMYL-6-METHOXY-2-PYRIDINECARBOXYLIC ACID METHYL ESTER;5-Formyl-6-methoxy-pyridine-2-carboxylic acid methyl ester;

Suppliers and Price of 2-Pyridinecarboxylic acid, 5-formyl-6-methoxy-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5-FORMYL-6-METHOXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER 95.00%
5MG
$ 497.74

Total 3 raw suppliers

Chemical Property of 2-Pyridinecarboxylic acid, 5-formyl-6-methoxy-, methyl ester

Chemical Property:

Boiling Point:355.4±42.0 °C(Predicted)
PSA：65.49000
Density:1.249±0.06 g/cm3(Predicted)
LogP:0.68930

Purity/Quality:

98%min ^*data from raw suppliers

5-FORMYL-6-METHOXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Pyridinecarboxylic acid, 5-formyl-6-methoxy-, methyl ester

There total 10 articles about 2-Pyridinecarboxylic acid, 5-formyl-6-methoxy-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

: 401792-84-5
methyl 5-(bromomethyl)-6-methoxy-2-pyridinecarboxylate

: 401792-87-8
methyl 5-formyl-6-methoxy-2-pyridinecarboxylate

Guidance literature:: With hexamethylenetetramine; In water; acetic acid; for 1h; Heating;
DOI:10.1016/S0957-4166(01)00414-1

Reference yield:

: 29681-38-7
methyl 5-methylpyridine-2-carboxylate

: 401792-87-8
methyl 5-formyl-6-methoxy-2-pyridinecarboxylate

Guidance literature:: Multi-step reaction with 5 steps

1.1: 78 percent / m-CPBA / CHCl₃ / 15 h / 20 °C

2.1: Ac₂O / 3 h / Heating

2.2: 51 percent / NaOMe / methanol / 0.17 h / 0 °C

3.1: 93 percent / Ag₂CO₃ / CHCl₃ / 120 h / 20 °C

4.1: 77 percent / AIBN; NBS / CCl₄ / Heating

5.1: 34 percent / hexamethylenetetramine; aq. acetic acid / 1 h / Heating

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); hexamethylenetetramine; acetic anhydride; acetic acid; 3-chloro-benzenecarboperoxoic acid; silver carbonate; In tetrachloromethane; chloroform; 5.1: Sommelet reaction;
DOI:10.1016/S0040-4020(02)00670-1

Reference yield:

: 67-56-1
methanol

: 201230-82-2
carbon monoxide

: 95652-81-6
6-chloro-2-methoxy-3-pyridinecarboxaldehyde

: 401792-87-8
methyl 5-formyl-6-methoxy-2-pyridinecarboxylate

Guidance literature:: With 1,1'-bis-(diphenylphosphino)ferrocene; sodium acetate; palladium diacetate; In toluene; at 50 ℃; for 23h;
DOI:10.1021/ol500529w