2,6-Diiodo-4-[(2-methyl-1-benzofuran-3-yl)methyl]phenol

Base Information

Chemical Name:2,6-Diiodo-4-[(2-methyl-1-benzofuran-3-yl)methyl]phenol
CAS No.:401917-61-1
Molecular Formula:C16H12I2O2
Molecular Weight:490.07400
Hs Code.:
DSSTox Substance ID:DTXSID60449895
Wikidata:Q82269433
Mol file:401917-61-1.mol

Synonyms:2,6-Diiodo-4-[(2-methyl-1-benzofuran-3-yl)methyl]phenol;401917-61-1;DTXSID60449895

Suppliers and Price of 2,6-Diiodo-4-[(2-methyl-1-benzofuran-3-yl)methyl]phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-[(3,5-DIIODO-4-HYDROXYPHENYL)METHYL]-2-METHYLBENZOFURAN 95.00%
5MG
$ 498.45

Total 1 raw suppliers

Chemical Property of 2,6-Diiodo-4-[(2-methyl-1-benzofuran-3-yl)methyl]phenol

Chemical Property:

PSA：33.37000
LogP:5.24680
XLogP3:5.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:489.89267
Heavy Atom Count:20
Complexity:326

Purity/Quality:: 3-[(3,5-DIIODO-4-HYDROXYPHENYL)METHYL]-2-METHYLBENZOFURAN 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C2=CC=CC=C2O1)CC3=CC(=C(C(=C3)I)O)I

Technology Process of 2,6-Diiodo-4-[(2-methyl-1-benzofuran-3-yl)methyl]phenol

There total 2 articles about 2,6-Diiodo-4-[(2-methyl-1-benzofuran-3-yl)methyl]phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4-(2-methyl-benzofuran-3-ylmethyl)-phenol

: 401917-61-1
2-methyl-3-(3,5-diiodo-4-hydroxybenzyl)benzofuran

Guidance literature:: With morpholine; tetramethylammonium dichloroiodate; In methanol; at 20 - 30 ℃; for 1h;
DOI:10.1021/jm001126+

Reference yield:

: 100-07-2
4-methoxy-benzoyl chloride

: 401917-61-1
2-methyl-3-(3,5-diiodo-4-hydroxybenzyl)benzofuran

Guidance literature:: Multi-step reaction with 4 steps

1: 63 percent / SnCl₄ / CH₂Cl₂ / 5 °C

2: NaBH₄; ZnI₂ / 1,2-dichloro-ethane / 2.25 h / 70 °C

3: pyridine hydrochloride / 2 h / 190 °C

4: 429 g / ICI*tetramethylammonium chloride; morpholine / methanol / 1 h / 20 - 30 °C

With morpholine; sodium tetrahydroborate; tetramethylammonium dichloroiodate; pyridine hydrochloride; tin(IV) chloride; zinc(II) iodide; In methanol; dichloromethane; 1,2-dichloro-ethane; 1: Friedel-Crafts acylation;
DOI:10.1021/jm001126+