diethyl 3,3,5,5-tetrakis(2-cyanoethyl)-4-oxo-cyclohexane-1,1-dicarboxy late

Base Information

• Chemical Name: diethyl 3,3,5,5-tetrakis(2-cyanoethyl)-4-oxo-cyclohexane-1,1-dicarboxy late
• CAS No.: 5408-02-6
• Molecular Formula: C24H30N4O5
• Molecular Weight: 0
• Hs Code.: 2926909090
• Mol file: 5408-02-6.mol

Synonyms:3,3,5,5-tetrakis-(2-cyano-ethyl)-4-oxo-cyclohexane-1,1-dicarboxylic acid diethyl ester;3,3,5,5-Tetrakis-(2-cyan-aethyl)-4-oxo-cyclohexan-1,1-dicarbonsaeure-diaethylester;

Chemical Property of diethyl 3,3,5,5-tetrakis(2-cyanoethyl)-4-oxo-cyclohexane-1,1-dicarboxy late

Chemical Property:

• Vapor Pressure: 8.4E-18mmHg at 25°C
• Boiling Point: 669.8°C at 760 mmHg
• Flash Point: 282.3°C
• PSA: 164.83000
• Density: 1.146g/cm³
• LogP: 3.64982

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of diethyl 3,3,5,5-tetrakis(2-cyanoethyl)-4-oxo-cyclohexane-1,1-dicarboxy late

There total 3 articles about diethyl 3,3,5,5-tetrakis(2-cyanoethyl)-4-oxo-cyclohexane-1,1-dicarboxy late which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl 2,2-bis(2-cyanoethyl)malonate (1444-05-9) → 3,3,5,5-tetrakis-(2-cyano-ethyl)-4-oxo-cyclohexane-1,1-dicarboxylic acid diethyl ester (5408-02-6)

Guidance literature:

Multi-step reaction with 3 steps

1: concentrated aqueous hydrochloric acid

2: PbO

3: benzyl-trimethyl-ammonium hydroxide

With hydrogenchloride; lead(II) oxide; N-benzyl-trimethylammonium hydroxide;

DOI:10.1021/jo01364a016

Reference yield:

pentane-1,3,3,5-tetracarboxylic acid-3,3-diethyl ester (92454-00-7) → 3,3,5,5-tetrakis-(2-cyano-ethyl)-4-oxo-cyclohexane-1,1-dicarboxylic acid diethyl ester (5408-02-6)

Guidance literature:

Multi-step reaction with 2 steps

1: PbO

2: benzyl-trimethyl-ammonium hydroxide

With lead(II) oxide; N-benzyl-trimethylammonium hydroxide;

DOI:10.1021/jo01364a016

Reference yield:

4-oxo-cyclohexane-1,1-dicarboxylic acid diethyl ester (55704-60-4) + acrylonitrile (107-13-1,25014-41-9) → 3,3,5,5-tetrakis-(2-cyano-ethyl)-4-oxo-cyclohexane-1,1-dicarboxylic acid diethyl ester (5408-02-6)

Guidance literature:

With N-benzyl-trimethylammonium hydroxide;

DOI:10.1021/jo01364a016

upstream raw materials:

4-oxo-cyclohexane-1,1-dicarboxylic acid diethyl ester

acrylonitrile

diethyl 2,2-bis(2-cyanoethyl)malonate

pentane-1,3,3,5-tetracarboxylic acid-3,3-diethyl ester

Downstream raw materials:

3,3,5,5-tetrakis-(2-carboxy-ethyl)-4-oxo-cyclohexanecarboxylic acid