4-(Acetyloxy)proline

Base Information

Chemical Name:4-(Acetyloxy)proline
CAS No.:25323-55-1
Molecular Formula:C7H11NO4
Molecular Weight:173.1665
Hs Code.:
NSC Number:118117
DSSTox Substance ID:DTXSID90948169
Mol file:25323-55-1.mol

Synonyms:25323-55-1;4-Acetoxypyrrolidine-2-carboxylic acid;4-(Acetyloxy)proline;NSC118117;4-(Acetyloxy)proline #;O-Acetyl-4-hydroxyproline;SCHEMBL3450044;DTXSID90948169;OQWHXHYZFMIILA-UHFFFAOYSA-N;NSC-118117

Suppliers and Price of 4-(Acetyloxy)proline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 4-(Acetyloxy)proline

Chemical Property:

Vapor Pressure:0.000121mmHg at 25°C
Boiling Point:311.8°Cat760mmHg
Flash Point:142.4°C
PSA：75.63000
Density:1.3g/cm³
LogP:-0.30660
Storage Temp.:-20°C
XLogP3:-2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:173.06880783
Heavy Atom Count:12
Complexity:204

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OC1CC(NC1)C(=O)O

Technology Process of 4-(Acetyloxy)proline

There total 5 articles about 4-(Acetyloxy)proline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.5%

: 142896-74-0
(2R,4S)-4-acetoxy-1,2-pyrrolidinedicarboxylic acid 1,2bis(phenylmethyl) ester

: 142796-93-8,25323-55-1
(2R,4S)-4-acetoxy-D-proline

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol;
DOI:10.1021/jm00093a024

Reference yield:

: Potassium; (2R,4R)-1-benzyloxycarbonyl-4-hydroxy-pyrrolidine-2-carboxylate

: 142796-93-8,25323-55-1
(2R,4S)-4-acetoxy-D-proline

Guidance literature:: Multi-step reaction with 4 steps

1: N,N-dimethyl-acetamide

2: pyridine

4: H₂ / 10percent Pd/C

With pyridine; hydrogen; palladium on activated charcoal; In N,N-dimethyl acetamide;
DOI:10.3987/COM-92-5984

Reference yield:

: 142776-07-6
(2R,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylic acid 1,2-bis(phenylmethyl) ester

: 142796-93-8,25323-55-1
(2R,4S)-4-acetoxy-D-proline

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine

3: H₂ / 10percent Pd/C

With pyridine; hydrogen; palladium on activated charcoal;
DOI:10.3987/COM-92-5984