DESETHYLENE CIPROFLOXACIN

Base Information

• Chemical Name: DESETHYLENE CIPROFLOXACIN
• CAS No.: 103222-12-4
• Molecular Formula: C15H16 F N3 O3
• Molecular Weight: 305.309
• Mol file: 103222-12-4.mol

Synonyms:BAY-r 3964;Ciprofloxacin metabolite 1; Desethyleneciprofloxacin; M1-Ciprofloxacin

Chemical Property of DESETHYLENE CIPROFLOXACIN

Chemical Property:

• Vapor Pressure: 6.13E-13mmHg at 25°C
• Boiling Point: 550.2°Cat760mmHg
• PKA: 6.40±0.41(Predicted)
• Flash Point: 286.5°C
• PSA: 74.57000
• Density: 1.541g/cm³
• LogP: 1.17920

Purity/Quality:

HPLC≥98% ^*data from raw suppliers

Ciprofloxacin-7-ethylenediamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DESETHYLENE CIPROFLOXACIN

There total 8 articles about DESETHYLENE CIPROFLOXACIN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ciprofloxacin (85721-33-1,178489-05-9,189257-90-7) → dichloroacetonitrile (3018-12-0) + C17H20FN3O3 + C15H17N3O5 + 7-amino-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid + chloral (75-87-6) + Desethyleneciprofloxacin (103222-12-4,178489-07-1) + 1-cyclopropyl-6-fluoro-7-amino-1,4-dihydro-4-oxoquinoline-3-carboxylic acid (105674-91-7)

Guidance literature:

With water; chlorine; for 0.15h; pH=7; Reagent/catalyst; pH-value; Kinetics; UV-irradiation; Photolysis;

DOI:10.1016/j.jphotochem.2018.10.043

Reference yield:

N-nitrosociprofloxacin (864443-44-7) → ciprofloxacin (85721-33-1,178489-05-9,189257-90-7) + Desethyleneciprofloxacin (103222-12-4,178489-07-1) + 1-cyclopropyl-6-fluoro-7-amino-1,4-dihydro-4-oxoquinoline-3-carboxylic acid (105674-91-7)

Guidance literature:

In water; at 30 ℃; for 2.5h; Time; Kinetics; Photolysis; UV-irradiation;

DOI:10.1016/j.watres.2020.116293

Reference yield:

ciprofloxacin (85721-33-1,178489-05-9,189257-90-7) → C15H17N3O4 (226903-16-8) + C13H11NO4 + Desethyleneciprofloxacin (103222-12-4,178489-07-1)

Guidance literature:

With sulfuric acid; ferrous ammonium sulphate hexahydrate; dihydrogen peroxide; In water; at 25 ℃; pH=3.5; pH-value;

DOI:10.1039/c3ra45709e

upstream raw materials:

ciprofloxacin hydrochloride

ciprofloxacin

1-cyclopropyl-6,7-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid

Refernces

• 1、 Deng, Jia,Wu, Guangxue,Yuan, Shoujun,Zhan, Xinmin,Wang, Wei,Hu, Zhen-Hu. "Ciprofloxacin degradation in UV/chlorine advanced oxidation process: Influencing factors, mechanisms and degradation pathways". . p. 151 - 158. Retrieved 2019.
• 2、 Giri, Ardhendu Sekhar,Golder, Animes Kumar. "Ciprofloxacin degradation from aqueous solution by Fenton oxidation: Reaction kinetics and degradation mechanisms". . p. 6738 - 6745. Retrieved 2014/02/14.