3-Pyridinecarboxylic acid, 2-amino-6-[2-[(4-methoxyphenyl)methoxy]phenyl]-4-[1-[(phenylmethoxy) carbonyl]-3-piperidinyl]-, 1,1-dimethylethyl ester

Base Information

• Chemical Name: 3-Pyridinecarboxylic acid, 2-amino-6-[2-[(4-methoxyphenyl)methoxy]phenyl]-4-[1-[(phenylmethoxy) carbonyl]-3-piperidinyl]-, 1,1-dimethylethyl ester
• CAS No.: 405239-74-9
• Molecular Formula: C37H41N3O6
• Molecular Weight: 623.749

Synonyms:

Chemical Property of 3-Pyridinecarboxylic acid, 2-amino-6-[2-[(4-methoxyphenyl)methoxy]phenyl]-4-[1-[(phenylmethoxy) carbonyl]-3-piperidinyl]-, 1,1-dimethylethyl ester

Chemical Property:

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Technology Process of 3-Pyridinecarboxylic acid, 2-amino-6-[2-[(4-methoxyphenyl)methoxy]phenyl]-4-[1-[(phenylmethoxy) carbonyl]-3-piperidinyl]-, 1,1-dimethylethyl ester

There total 1 articles about 3-Pyridinecarboxylic acid, 2-amino-6-[2-[(4-methoxyphenyl)methoxy]phenyl]-4-[1-[(phenylmethoxy) carbonyl]-3-piperidinyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cyanoacetic acid tert-butyl ester (1116-98-9) + 1-Benzyloxycarbonylpiperidine-3-carboxaldehyde (201478-72-0,405063-39-0) + 1-(2-((4-methoxybenzyl)oxy)phenyl)ethanone (371258-91-2) → tert-butyl 2-amino-4-{1-[(benzyloxy)carbonyl]-3-piperidinyl}-6-{2-[(4-methoxybenzyl)oxy]phenyl}nicotinate (405239-74-9)

Guidance literature:

With ammonium acetate; In 1,2-dimethoxyethane;

Reference yield:

tert-butyl 2-amino-4-{1-[(benzyloxy)carbonyl]-3-piperidinyl}-6-{2-[(4-methoxybenzyl)oxy]phenyl}nicotinate (405239-74-9) → 2-amino-4-{1-[(benzyloxy)carbonyl]-3-piperidinyl}-6-(2-hydroxyphenyl)nicotinic acid (406212-78-0)

Guidance literature:

With trifluoroacetic acid; In dichloromethane;

upstream raw materials:

cyanoacetic acid tert-butyl ester

1-Benzyloxycarbonylpiperidine-3-carboxaldehyde

1-(2-((4-methoxybenzyl)oxy)phenyl)ethanone

Downstream raw materials:

2-amino-4-{1-[(benzyloxy)carbonyl]-3-piperidinyl}-6-(2-hydroxyphenyl)nicotinic acid

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