2-methyl-5,6-dihydro-1,3-thiazino(2,3-b)quinazolin-4-one

Base Information

Chemical Name:2-methyl-5,6-dihydro-1,3-thiazino(2,3-b)quinazolin-4-one
CAS No.:85852-71-7
Molecular Formula:C₁₂H₁₀N₂OS
Molecular Weight:230.29
Hs Code.:2934999090
Mol file:85852-71-7.mol

Synonyms:2-methyl-5,6-dihydro-1,3-thiazino(2,3-b)quinazolin-4-one

Suppliers and Price of 2-methyl-5,6-dihydro-1,3-thiazino(2,3-b)quinazolin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 4 raw suppliers

Chemical Property of 2-methyl-5,6-dihydro-1,3-thiazino(2,3-b)quinazolin-4-one

Chemical Property:

Vapor Pressure:1.13E-06mmHg at 25°C
Boiling Point:402°C at 760 mmHg
Flash Point:196.9°C
PSA：62.60000
Density:1.38g/cm³
LogP:1.24790

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-methyl-5,6-dihydro-1,3-thiazino(2,3-b)quinazolin-4-one

There total 4 articles about 2-methyl-5,6-dihydro-1,3-thiazino(2,3-b)quinazolin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 22820-08-2
3,4-dihydro-1H-quinazoline-2-thione

: 6127-93-1
3-chlorocrotonic acid ethyl ester

: 85852-71-7
2-Methyl-5,6-dihydro-4(H)-oxo-1,3-thiazino<2,3-b>chinazolin

Guidance literature:: With sodium ethanolate; In ethanol; 1.) R_.T_., 1 h, 2.) reflux, 5 h;
DOI:10.1002/ardp.19833160418

Reference yield:

: 4403-69-4
2-amino-1-benzylamine

: 85852-71-7
2-Methyl-5,6-dihydro-4(H)-oxo-1,3-thiazino<2,3-b>chinazolin

Guidance literature:: Multi-step reaction with 2 steps

1: base

With base;

Reference yield:

: 1885-29-6
anthranilic acid nitrile

: 85852-71-7
2-Methyl-5,6-dihydro-4(H)-oxo-1,3-thiazino<2,3-b>chinazolin

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / LiAlH₄ / tetrahydrofuran

2: 88 percent / KOH / ethanol

3: 42 percent / C₂H₅ONa / ethanol / 1.) R_.T_., 1 h, 2.) reflux, 5 h

With potassium hydroxide; lithium aluminium tetrahydride; sodium ethanolate; In tetrahydrofuran; ethanol;
DOI:10.1002/ardp.19833160418