1,2-Bis(2-propynyloxy)ethane

Base Information

• Chemical Name: 1,2-Bis(2-propynyloxy)ethane
• CAS No.: 40842-04-4
• Molecular Formula: C8H10O2
• Molecular Weight: 138.166
• European Community (EC) Number: 808-107-1
• DSSTox Substance ID: DTXSID501174405
• Nikkaji Number: J1.973.781K
• Mol file: 40842-04-4.mol

Synonyms:40842-04-4;1,2-Bis(2-propynyloxy)ethane;Bis-propargyl-PEG1;Ethylene Glycol 1,2-Bis(2-propynyl) Ether;1,2-Bis(propargyloxy)ethane;Alkyne-PEG2-Alkyne;1,2-bis(prop-2-yn-1-yloxy)ethane;4,7-Dioxa-1,9-decadiyne;Propargyl-PEG2-Propargyl;Ethylene glycol dipropargyl ether;3-(2-prop-2-ynoxyethoxy)prop-1-yne;EthyleneGlycol1,2-Bis(2-propynyl)Ether;1-Propyne, 3,3'-[1,2-ethanediylbis(oxy)]bis-;LCWG012;SCHEMBL9492835;AMY4471;Bis-propargyl-PEG, MW 1,000;Bis-propargyl-PEG, MW 3,400;Bis-propargyl-PEG, MW 5,000;DTXSID501174405;Bis-propargyl-PEG, MW 10,000;MFCD03640302;ethylene glycol bis(2-propynyl) ether;s10506;BP-21675;BP-25843;BP-25846;BP-28783;BP-28784;BS-28372;HY-140038;CS-0114310;E1054;3-[2-(PROP-2-YN-1-YLOXY)ETHOXY]PROP-1-YNE

Chemical Property of 1,2-Bis(2-propynyloxy)ethane

Chemical Property:

• Refractive Index: 1.4550 to 1.4590
• Boiling Point: 88°C/15mmHg(lit.)
• PSA: 18.46000
• LogP: 0.28600
• Solubility.: Soluble in DMSO, DCM, DMF
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 138.068079557
• Heavy Atom Count: 10
• Complexity: 135

Purity/Quality:

98%,99%, ^*data from raw suppliers

bis-Propargyl-PEG2 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C#CCOCCOCC#C
• Description: Bis-propargyl-PEG2 is a homobifunctional PEG linker with two propargyl groups. The propargyl groups forms triazole linkage with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry.

Technology Process of 1,2-Bis(2-propynyloxy)ethane

There total 9 articles about 1,2-Bis(2-propynyloxy)ethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

ethylene glycol (107-21-1) + 2-propynyl chloride (624-65-7) → α,ω-bis(O-propargyl)ethylene glycol (40842-04-4)

Guidance literature:

With potassium hydroxide; In dimethyl sulfoxide; at 29 - 32 ℃; for 2h;

Reference yield: 80.2%

2-(prop-2-ynyloxy)ethanol (3973-18-0) + propargyl bromide (106-96-7) → α,ω-bis(O-propargyl)ethylene glycol (40842-04-4)

Guidance literature:

With N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide; at 50 - 60 ℃; for 3h;

DOI:10.1134/S1070427210110121

Reference yield: 71.0%

ethylene glycol (107-21-1) + propargyl bromide (106-96-7) → α,ω-bis(O-propargyl)ethylene glycol (40842-04-4)

Guidance literature:

ethylene glycol; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃;

propargyl bromide; In N,N-dimethyl-formamide; at 0 - 20 ℃;

DOI:10.1039/b822976g

upstream raw materials:

bromo-1 propargyloxy-2 ethane

2-(prop-2-ynyloxy)ethanol

2-propynyl chloride

ethylene glycol

Downstream raw materials:

C₁₂H₁₈O₄

1-methoxy-4-[2-(prop-2-ynyloxy)ethoxy]but-2-yne

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 40842-04-4 Ethylene Glycol 1,2-Bis(2-propynyl) Ether

Send

Send

Metric Ton KG G Pound L ML

Send

Send