4-Piperidinebutanoic acid, methyl ester

Base Information

• Chemical Name: 4-Piperidinebutanoic acid, methyl ester
• CAS No.: 408538-69-2
• Molecular Formula: C10H19NO2
• Molecular Weight: 185.266
• Mol file: 408538-69-2.mol

Synonyms:4-piperidin-4-ylbutyric acid methyl ester;4-Piperidinebutanoic acid,methyl ester;

Chemical Property of 4-Piperidinebutanoic acid, methyl ester

Chemical Property:

• PSA: 38.33000
• LogP: 1.65810

Purity/Quality:

99% ^*data from raw suppliers

4-PIPERIDINEBUTANOIC ACID METHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Piperidinebutanoic acid, methyl ester

There total 1 articles about 4-Piperidinebutanoic acid, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 3-((4-(4-methoxy-4-oxobutyl)piperidin-1-yl)diazenyl)benzoate (1428864-65-6) → benzoic acid methyl ester (93-58-3,5705-52-2,80226-58-0) + 4-piperidin-4-ylbutyric acid methyl ester (408538-69-2)

Guidance literature:

With trichlorosilane; In acetonitrile; Reagent/catalyst; Solvent;

DOI:10.1039/c3ob27504c

Reference yield: 68.0%

4-piperidin-4-ylbutyric acid methyl ester (408538-69-2) + benzoyl chloride (98-88-4) → methyl 4-(1-benzoylpiperidin-4-yl)butanoate (1296136-93-0)

Guidance literature:

With pyridine; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1016/j.ejmech.2011.01.034

Reference yield: 68.0%

C44H34N6SO11 (909258-98-6) + 4-piperidin-4-ylbutyric acid methyl ester (408538-69-2) → C50H48N6SO10 (909259-04-7)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

DOI:10.1021/ac060764i

upstream raw materials:

methyl 3-((4-(4-methoxy-4-oxobutyl)piperidin-1-yl)diazenyl)benzoate

Downstream raw materials:

C₅₀H₄₈N₆SO₁₀

[4-(4-aminobutyl)-1-piperidinyl](phenyl)methenone

(E)-N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(3-nitrophenyl)acrylamide

(E)-N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(1-(4-hydroxy-3-(hydroxymethyl)butyl)-1H-pyrrol-2-yl)acrylamide