N-Ethyl-3-methoxyaniline

Base Information

• Chemical Name: N-Ethyl-3-methoxyaniline
• CAS No.: 41115-30-4
• Molecular Formula: C9H13NO
• Molecular Weight: 151.208
• Hs Code.: 2922299090
• Mol file: 41115-30-4.mol

Synonyms:N-ethyl-m-anisidine;ethyl(3-methoxyphenyl)amine;(R)-(3-methoxyphenyl)ethylamine;N-Ethyl-N-(3-methoxyphenyl)amine;3-methoxy-N-ethylaniline;Benzenamine,N-ethyl-3-methoxy;meta-methoxyphenylethylamine;

Chemical Property of N-Ethyl-3-methoxyaniline

Chemical Property:

• Boiling Point: 255.6±23.0 °C(Predicted)
• PKA: 4.86±0.25(Predicted)
• PSA: 21.26000
• Density: 1.012±0.06 g/cm3(Predicted)
• LogP: 2.20000

Purity/Quality:

99% ^*data from raw suppliers

N-Ethyl-3-methoxy-benzenamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N-Ethyl-3-methoxy-benzenamine is a useful research chemical.

Technology Process of N-Ethyl-3-methoxyaniline

There total 18 articles about N-Ethyl-3-methoxyaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

rac-cysteine (921-01-7,3374-22-9,4371-52-2,40143-64-4,40143-66-6,40143-69-9,52-90-4) + N-ethyl-N-(3-methoxyphenyl)-2,4-dinitrobenzenesulfonamide → S-(2,4-Dinitrophenyl)-cystein (3165-76-2) + N-ethyl-m-anisidine (41115-30-4) + sulfur dioxide (7446-09-5,12143-17-8,89125-89-3)

Guidance literature:

In aq. phosphate buffer; for 0.5h; pH=7.4;

DOI:10.1016/j.bmcl.2015.04.046

Reference yield: 96.0%

m-methoxyacetanilide (588-16-9) → N-ethyl-m-anisidine (41115-30-4)

Guidance literature:

With borane-THF; In tetrahydrofuran; at 5 - 20 ℃; for 24.5h; Inert atmosphere;

Reference yield: 96.0%

3-nitroanisole (555-03-3) + acetaldehyde (75-07-0,9002-91-9) → N-ethyl-m-anisidine (41115-30-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide; for 8h;

DOI:10.1016/j.tetlet.2007.12.030

upstream raw materials:

ethyl bromide

m-Anisidine

diethyl sulfate

m-methoxyacetanilide

Downstream raw materials:

sodium salt of N-ethyl-N-(2-hydroxy-3-sulfopropyl)-m-anisidine