2-Chloro-1-(4-methylpiperazin-1-yl)ethanone hydrochloride

Base Information

Chemical Name:2-Chloro-1-(4-methylpiperazin-1-yl)ethanone hydrochloride
CAS No.:42951-91-7
Molecular Formula:C7H13ClN2O.ClH
Molecular Weight:213.107
Hs Code.:
European Community (EC) Number:840-984-6,673-877-6
Mol file:42951-91-7.mol

Synonyms:40340-73-6;2-chloro-1-(4-methylpiperazin-1-yl)ethanone hydrochloride;42951-91-7;1-(2-Chloroacetyl)-4-methylpiperazine HCl;1-(chloroacetyl)-4-methylpiperazine hydrochloride;2-chloro-1-(4-methyl-piperazin-1-yl)-ethanone hydrochloride;2-chloro-1-(4-methylpiperazin-1-yl)ethanone;hydrochloride;1-(2-chloroacetyl)-4-methyl-piperazine hcl;1-(2-CHLOROACETYL)-4-METHYL-PIPERAZINEHCL;1-(2-Chloroacetyl)-4-methyl-piperazine hydrochloride;MFCD04113883;1-(2-Chloroacetyl)-4-methylpiperazine hydrochloride;2-chloro-1-(4-methylpiperazin-1-yl)ethan-1-one hydrochloride;1-(2-chloroacetyl)-4-methyl-piperazinehydrochloride;C7H14Cl2N2O;SCHEMBL6031483;2-chloro-1-(4-methyl-1-piperazinyl)ethanone hydrochloride;Piperazine, 1-(chloroacetyl)-4-methyl-, monohydrochloride;XFUOEOASGSUIBP-UHFFFAOYSA-N;AKOS000283739;AS-48448;1-(2-Chloroacetyl)-4-methylpiperazineHCl;S-Pyrrolidine-2-carbonitrile hydrochloride;CS-0205601;FT-0678367;EN300-09409;1-(2-Chloroacetyl)-4-methyl-piperazine x HCl;F31062;A825061;1-(2-chloro-acetyl)-4-methyl-piperazine hydrochloride;Z1741967270;2-Chloro-1-(4-methylpiperazin-1-yl)-ethanone hydrochloride;2-chloro-1-(4-methylpiperazin-1-yl)ethanone, hydrochloride;2-chloranyl-1-(4-methylpiperazin-1-yl)ethanone hydrochloride

Suppliers and Price of 2-Chloro-1-(4-methylpiperazin-1-yl)ethanone hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(2-Chloroacetyl)-4-methylpiperazinehydrochloride
250mg
$ 70.00

ChemBridge Corporation
1-(chloroacetyl)-4-methylpiperazinehydrochloride 95%
5 g
$ 205.00

AK Scientific
1-(2-Chloroacetyl)-4-methylpiperazineHCl
1g
$ 191.00

Total 5 raw suppliers

Chemical Property of 2-Chloro-1-(4-methylpiperazin-1-yl)ethanone hydrochloride

Chemical Property:

Melting Point:212-213 °C(Solv: methanol (67-56-1); ethanol (64-17-5))
PSA：23.55000
LogP:0.67700
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:212.0483185
Heavy Atom Count:12
Complexity:143

Purity/Quality:

99% ^*data from raw suppliers

1-(2-Chloroacetyl)-4-methylpiperazinehydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCN(CC1)C(=O)CCl.Cl
Uses 1-(2-Chloroacetyl)-4-methylpiperazine HCl

Technology Process of 2-Chloro-1-(4-methylpiperazin-1-yl)ethanone hydrochloride

There total 1 articles about 2-Chloro-1-(4-methylpiperazin-1-yl)ethanone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 109-01-3
1-methyl-piperazine

: 79-04-9
chloroacetyl chloride

: 42951-91-7
2-chloro-1-(4-methylpiperazin-1-yl)ethan-1-one hydrochloride

Guidance literature:: With potassium carbonate; In chloroform; at 20 - 25 ℃; for 2h;

Reference yield: 79.0%

: 1428847-58-8
benzyl 4-methoxy-3-(methylsulfonamido)benzoate

: 42951-91-7
2-chloro-1-(4-methylpiperazin-1-yl)ethan-1-one hydrochloride

: 1610862-15-1
benzyl 4-methoxy-3-(N-(2-(4-methylpiperazin-1-yl)-2-oxoethyl)methylsulfonamido)benzoate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 70 ℃; for 1h;

Reference yield: 78.0%

: C₁₆H₂₃NO₄

: 42951-91-7
2-chloro-1-(4-methylpiperazin-1-yl)ethan-1-one hydrochloride

: tert-butyl 2-(3-(methoxymethoxy)phenyl)cyclopropyl(2-(4-methylpiperazin-1-yl)-2-oxoethyl)carbamate

Guidance literature:: C₁₆H₂₃NO₄; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.166667h;

2-chloro-1-(4-methylpiperazin-1-yl)ethan-1-one hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 12h;
DOI:10.1039/c4md00330f