2H-1-Benzopyran-2-carboxamide, 3,4-dihydro-, (2R)-

Base Information

Chemical Name:2H-1-Benzopyran-2-carboxamide, 3,4-dihydro-, (2R)-
CAS No.:437763-61-6
Molecular Formula:C10H11NO2
Molecular Weight:177.203
Hs Code.:
DSSTox Substance ID:DTXSID90433106
Nikkaji Number:J2.058.275H
Wikidata:Q82247232
Mol file:437763-61-6.mol

Synonyms:2H-1-Benzopyran-2-carboxamide, 3,4-dihydro-, (2R)-;437763-61-6;SCHEMBL4934593;DTXSID90433106;(2R)-3,4-Dihydro-2H-1-benzopyran-2beta-carboxamide

Suppliers and Price of 2H-1-Benzopyran-2-carboxamide, 3,4-dihydro-, (2R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of 2H-1-Benzopyran-2-carboxamide, 3,4-dihydro-, (2R)-

Chemical Property:

PSA：53.31000
LogP:2.01520
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:177.078978594
Heavy Atom Count:13
Complexity:205

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC2=CC=CC=C2OC1C(=O)N
Isomeric SMILES:C1CC2=CC=CC=C2O[C@H]1C(=O)N

Technology Process of 2H-1-Benzopyran-2-carboxamide, 3,4-dihydro-, (2R)-

There total 2 articles about 2H-1-Benzopyran-2-carboxamide, 3,4-dihydro-, (2R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 4-((2R)-2-{[[(2S)-2-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}-3-(phenyloxy)propyl](phenylmethyl)amino]methyl}-3,4-dihydro-2H-chromen-6-yl)-2-pyridinecarboxylic acid

: 437763-61-6
(R)-chroman-2-carboxylic acid amide

Guidance literature:

Reference yield:

: 24698-77-9
ethyl Chroman-2-carboxylate

: 437763-61-6
(R)-chroman-2-carboxylic acid amide

Guidance literature:: Multi-step reaction with 2 steps

1: lipase from Pseudomonas fluorescens; sodium hydroxide / tetrahydrofuran; water / 20 °C / pH 8 / aq. phosphate buffer; Enzymatic reaction

2: ammonia; ammonium chloride / water / 2 h / 100 °C

With lipase from Pseudomonas fluorescens; ammonia; ammonium chloride; sodium hydroxide; In tetrahydrofuran; water;
DOI:10.1021/jm2007886

Reference yield: 87.0%

: 437763-61-6
(R)-chroman-2-carboxylic acid amide

: 149177-75-3,437763-66-1
(2R)-3,4-dihydro-2H-chromen-2-ylmethylamine hydrochloride

Guidance literature:: (R)-chroman-2-carboxylic acid amide; With dimethylsulfide borane complex; In tetrahydrofuran; Heating;

With hydrogenchloride; In methanol; diethyl ether; Further stages.;
DOI:10.1016/j.tetlet.2004.05.037