methyl 2-phenylpent-4-enoate

Base Information

• Chemical Name: methyl 2-phenylpent-4-enoate
• CAS No.: 14815-73-7
• Molecular Formula: C12H14O2
• Molecular Weight: 190.242
• Mol file: 14815-73-7.mol

Synonyms:

Chemical Property of methyl 2-phenylpent-4-enoate

Chemical Property:

• Vapor Pressure: 0.0436mmHg at 25°C
• Boiling Point: 237.9°Cat760mmHg
• Flash Point: 90.7°C
• Density: 1.014g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-phenylpent-4-enoate

There total 21 articles about methyl 2-phenylpent-4-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

allyl bromide (106-95-6) + benzeneacetic acid methyl ester (101-41-7) → methyl allylphenylacetate (14815-73-7)

Guidance literature:

benzeneacetic acid methyl ester; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

allyl bromide; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 6h; Further stages.;

DOI:10.1021/ja002496q

Reference yield: 91.0%

diallylcarbonate (15022-08-9) + benzeneacetic acid methyl ester (101-41-7) → methyl allylphenylacetate (14815-73-7)

Guidance literature:

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; 1,2-bis-(diphenylphosphino)ethane; In tetrahydrofuran; at 65 ℃; for 1h;

DOI:10.1021/jo00209a032

Reference yield: 83.0%

methanol (67-56-1) + 2-phenyl-pent-4-enoic acid (1575-70-8) → methyl allylphenylacetate (14815-73-7)

Guidance literature:

With sulfuric acid; for 16h; Reflux;

DOI:10.1007/s00706-012-0905-3

upstream raw materials:

diazomethane

phenylacetic acid

allyl bromide

benzeneacetic acid methyl ester

Downstream raw materials:

benzeneacetic acid methyl ester

3-phenyl-5-methyl-2,5-dihydrofuran-2-one

benzoic acid

methyl 8-(methylsulfonyloxy)-2,7-diphenyloct-4-enoate

Refernces

• 1、 Campano, Teresa E.,García-Urricelqui, Ane,Mielgo, Antonia,Palomo, Claudio,de Cózar, Abel. "syn-Selective Michael Reaction of α-Branched Aryl Acetaldehydes with Nitroolefins Promoted by Squaric Amino Acid Derived Bifunctional Br?nsted Bases". supporting information. p. 3604 - 3612. Retrieved 2021/07/26.
• 2、 Dechert-Schmitt, Anne-Marie,Cabral, Shawn,Kung, Daniel W.. "Development of an O-Vinylation-Ring-Closing Metathesis Strategy to Access 3,3′-3,4-Dihydropyrans". supporting information. p. 2611 - 2615. Retrieved 2016/11/11.