1-Bromo-2-(1,1-difluoroethyl)benzene

Base Information

Chemical Name:1-Bromo-2-(1,1-difluoroethyl)benzene
CAS No.:444581-46-8
Molecular Formula:C8H7BrF2
Molecular Weight:221.044
Hs Code.:2903998090
European Community (EC) Number:695-525-0
Mol file:444581-46-8.mol

Synonyms:1-Bromo-2-(1,1-difluoroethyl)benzene;444581-46-8;MFCD09996896;Benzene, 1-bromo-2-(1,1-difluoroethyl)-;1-bromo-2-(1,1-difluoro-ethyl)-benzene;SCHEMBL4123029;AMY5991;AKOS005257900;SB22934;2-(1,1-Difluoroethyl)-1-bromobenzene;MS-20193;DB-250333;CS-0068794;1-Bromo-2-(1,1-difluoroethyl)benzene, 97%;EN300-633500;F30206;1-Bromo-2-(1,1-difluoroethyl)benzene stabilized over potassium carbonate

Suppliers and Price of 1-Bromo-2-(1,1-difluoroethyl)benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Bromo-2-(1,1-difluoroethyl)benzene
100mg
$ 70.00

TRC
1-Bromo-2-(1,1-difluoroethyl)benzene
50mg
$ 50.00

Sigma-Aldrich
1-Bromo-2-(1,1-difluoroethyl)benzene 97%
1g
$ 135.00

Matrix Scientific
1-Bromo-2-(1,1-difluoroethyl)benzene 97%
500mg
$ 119.00

Matrix Scientific
1-Bromo-2-(1,1-difluoroethyl)benzene 97%
1g
$ 183.00

Chemenu
1-Bromo-2-(1,1-difluoroethyl)benzene 95%
5g
$ 622.00

Atlantic Research Chemicals
1-Bromo-2-(1,1-difluoroethyl)benzene 95%
1gm:
$ 123.71

Apolloscientific
1-Bromo-2-(1,1-difluoroethyl)benzene 97%
1g
$ 80.00

Apolloscientific
1-Bromo-2-(1,1-difluoroethyl)benzene 97%
5g
$ 283.00

Apolloscientific
1-Bromo-2-(1,1-difluoroethyl)benzene 97%
25g
$ 798.00

Total 7 raw suppliers

Chemical Property of 1-Bromo-2-(1,1-difluoroethyl)benzene

Chemical Property:

Refractive Index:n20/D 1.510
Flash Point:91°C
PSA：0.00000
Density:1.518g/mLat 25℃
LogP:3.56080
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:219.96992
Heavy Atom Count:11
Complexity:136

Purity/Quality:

97% ^*data from raw suppliers

1-Bromo-2-(1,1-difluoroethyl)benzene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi,N
Statements: 36-51/53
Safety Statements: 26-61

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=CC=C1Br)(F)F

Technology Process of 1-Bromo-2-(1,1-difluoroethyl)benzene

There total 2 articles about 1-Bromo-2-(1,1-difluoroethyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 2142-69-0
2-bromophenyl methyl ketone

: 444581-46-8
1-bromo-2-(1,1-difluoroethyl)benzene

Guidance literature:: With 4-tert-butyl-2,6-dimethylphenylsulfur trifluoride; pyridine hydrofluoride; In dichloromethane; at 23 ℃; for 18h;

Reference yield:

: 7073-69-0
2-(2-bromophenyl)propanol

: 444581-46-8
1-bromo-2-(1,1-difluoroethyl)benzene

Guidance literature:: With triethylamine tris(hydrogen fluoride); ethanaminium,N-(difluoro-λ⁴-sulfanylidene)-N-ethyl-,tetrafluoroborate; In dichloromethane; at 20 ℃; for 1h;
DOI:10.1021/acs.jmedchem.7b01682

Reference yield: 97.0%

: 444581-46-8
1-bromo-2-(1,1-difluoroethyl)benzene

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: C₉H₈F₂O

Guidance literature:: 1-bromo-2-(1,1-difluoroethyl)benzene; With n-butyllithium; In tetrahydrofuran; hexane; at -85 ℃; for 1.5h; Inert atmosphere;

N,N-dimethyl-formamide; In tetrahydrofuran; hexane; at -80 ℃; for 0.75h;