(1R,2R)-2-(Diphenylphosphino)cyclohexanamine

Base Information

• Chemical Name: (1R,2R)-2-(Diphenylphosphino)cyclohexanamine
• CAS No.: 452304-59-5
• Molecular Formula: C18H22NP
• Molecular Weight: 283.353
• DSSTox Substance ID: DTXSID20457456
• Nikkaji Number: J1.797.912D
• Wikidata: Q82280305
• Mol file: 452304-59-5.mol

Synonyms:(1R,2R)-2-(Diphenylphosphino)cyclohexanamine;452304-59-5;(1R,2R)-2-diphenylphosphanylcyclohexan-1-amine;(1R,2R)-2-(diphenylphosphanyl)cyclohexan-1-amine;(1R,2R)-2-(DIPHENYLPHOSPHINO)CYCLOHEXYLAMINE;SCHEMBL17513103;DTXSID20457456;CTA30459;MFCD17013996;AKOS016000552;CS-W014562;SC11603;AS-66444;D94670;A872410;(1R,2R)-2-(Diphenylphosphino)cyclohexylamine, 95%;(1R)-2alpha-(Diphenylphosphino)cyclohexane-1beta-amine;(1R,2R)-(-)-2-(DIPHENYLPHOSPHINO)CYCLOHEXYLAMINE;(1R,2R)-2-(DIPHENYLPHOSPHINO)-1-AMINOCYCLOHEXANE;(1R,2R)-2-(DIPHENYLPHOSPHINO)CYCLOHEXANAMINE

Chemical Property of (1R,2R)-2-(Diphenylphosphino)cyclohexanamine

Chemical Property:

• Melting Point: 43-48℃
• Boiling Point: 402.9±38.0 °C(Predicted)
• PKA: 9.87±0.70(Predicted)
• Flash Point: >110°(230°F)
• PSA: 39.61000
• LogP: 4.08950
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Sensitive.: Air Sensitive
• Water Solubility.: Insoluble in water.
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 283.148986704
• Heavy Atom Count: 20
• Complexity: 263

Purity/Quality:

97% ^*data from raw suppliers

(1R,2R)-2-(Diphenylphosphino)-1-aminocyclohexane, min. 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(C(C1)N)P(C2=CC=CC=C2)C3=CC=CC=C3
• Isomeric SMILES: C1CC[C@H]([C@@H](C1)N)P(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of (1R,2R)-2-(Diphenylphosphino)cyclohexanamine

There total 9 articles about (1R,2R)-2-(Diphenylphosphino)cyclohexanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

trans-1-amino-2-(diphenylphosphino)cyclohexane → (1R,2R)-2-amino-1-(diphenylphosphino)-cyclohexane (452304-59-5) + (1S,2S)-2-(diphenylphosphaneyl)cyclohexan-1-amine (452304-63-1)

Guidance literature:

trans-1-amino-2-(diphenylphosphino)cyclohexane; With D-tartaric acid; In water; at 80 ℃;

With sodium hydroxide; Further stages.;

DOI:10.1021/ol026249y

Reference yield: 64.0%

C23H33BNO2P → (1R,2R)-2-amino-1-(diphenylphosphino)-cyclohexane (452304-59-5)

Guidance literature:

With tetrafluoroboric acid diethyl ether; In dichloromethane; at -4 - 20 ℃; for 22h; Inert atmosphere;

DOI:10.1002/adsc.201200133

Reference yield:

trans-1-amino-2-(diphenylphosphino)cyclohexane → (1R,2R)-2-amino-1-(diphenylphosphino)-cyclohexane (452304-59-5)

Guidance literature:

With aq. D-tartaric acid; at 95 ℃;

DOI:10.1021/ja801344w

upstream raw materials:

7-azabicyclo[4.1.0]heptane

cyclohexane-1,2-epoxide

diphenylphosphane

1-nitrocyclohexene

Downstream raw materials:

C₃₆H₄₀N₃OPS

C₂₇H₂₅F₆N₂PS

C₂₅H₂₇N₂OP

C₂₅H₂₇N₂PS

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 452304-59-5 (1R,2R)-2-(Diphenylphosphino)-1-aminocyclohexane, min. 97%

Send

Send

Metric Ton KG G Pound L ML

Send

Send