Diflufenican

Base Information

Chemical Name:Diflufenican
CAS No.:83164-33-4
Molecular Formula:C19H11F5N2O2
Molecular Weight:394.301
Hs Code.:
European Community (EC) Number:617-446-2,953-443-5
UNII:3T8D1VDO6K
DSSTox Substance ID:DTXSID4041494
Nikkaji Number:J246.562K
Wikidata:Q424793
Pharos Ligand ID:JSHMNFMBKYMK
Metabolomics Workbench ID:87125
ChEMBL ID:CHEMBL1425995
Mol file:83164-33-4.mol

Synonyms:diflufenican

Suppliers and Price of Diflufenican

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AHH
Diflufenican 98%
5g
$ 800.00

AK Scientific
Diflufenican
1g
$ 49.00

American Custom Chemicals Corporation
DIFLUFENICAN 95.00%
10G
$ 890.00

American Custom Chemicals Corporation
DIFLUFENICAN 95.00%
1G
$ 449.00

Biosynth Carbosynth
Diflufenican
10 g
$ 1201.20

Biosynth Carbosynth
Diflufenican
5 g
$ 660.70

Biosynth Carbosynth
Diflufenican
500 mg
$ 115.00

Biosynth Carbosynth
Diflufenican
1 g
$ 199.90

Biosynth Carbosynth
Diflufenican
2 g
$ 363.40

Chemenu
N-(2,4-Difluorophenyl)-2-(3-(trifluoromethyl)-phenoxy)nicotinamide 97%
10g
$ 127.00

Total 103 raw suppliers

Chemical Property of Diflufenican

Chemical Property:

Appearance/Colour:odorlessness white solid
Vapor Pressure:7.39E-06mmHg at 25°C
Melting Point:159-161 °C
Refractive Index:1.573
Boiling Point:376.2 °C at 760 mmHg
PKA:9.03±0.70(Predicted)
Flash Point:181.3 °C
PSA：51.22000
Density:1.438 g/cm³
LogP:5.49620
Storage Temp.:0-6°C
Solubility.:Acetone (Slightly), Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly),
XLogP3:4.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:394.07406841
Heavy Atom Count:28
Complexity:533

Purity/Quality:

99% ^*data from raw suppliers

Diflufenican 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s): R52/53:;
Hazard Codes:R52/53:;
Statements: 52/53
Safety Statements: 61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F
Description The diflufenican is a selective contact and residual herbicide that can be applied pre-emergence and post-emergence. It can be absorbed through the shoots of the germinating seeding with limited translocation. Its mode of mechanism is via a bleaching action through inhibiting the carotenoid biosynthesis process, further blocking photosynthesis process and causing plant death. It is used for the treatment of some broad leaved weeds such as Stellaria media (Chickweed), Veronica Spp (Speedwell), Viola spp, Geranium spp (Cranesbill) and Laminum spp (Dead nettles). It has been approved for use on barley, durum wheat, rye, triticale and wheat. It can be used in combination with isoproturon or other cereal herbicides.
Uses Pre and post emergence foliar absorbed herbicide for winter weed control in cereal crops; carotenoid biosynthesis inhibitor. Herbicide.

Technology Process of Diflufenican

There total 7 articles about Diflufenican which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 367-25-9,76563-56-9
2,4-difluorophenylamine

: 36701-89-0
2-(3-Trifluoromethyl-phenoxy)-nicotinic acid

: 83164-33-4
N-(2,4-difluorophenyl)-2-(3-trifluoromethylphenoxy)-3-pyridinecarboxamide

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; Cooling with ice;

Reference yield: 33.0%

: 197565-66-5
3-chloro-2-[3-(trifluoromethyl)phenoxy]pyridine

: 201230-82-2
carbon monoxide

: 367-25-9,76563-56-9
2,4-difluorophenylamine

: 83164-33-4
N-(2,4-difluorophenyl)-2-(3-trifluoromethylphenoxy)-3-pyridinecarboxamide

Guidance literature:: With sodium carbonate; bis-triphenylphosphine-palladium(II) chloride; 1,4-di(diphenylphosphino)-butane; In xylene; at 190 - 195 ℃; for 19h; under 11251.1 Torr;

Reference yield:

: 1570135-74-8
N-(2-(4,5-dihydrooxazol-2-yl)phenyl)nicotinamide

: 83164-33-4
N-(2,4-difluorophenyl)-2-(3-trifluoromethylphenoxy)-3-pyridinecarboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: sodium carbonate / dimethyl sulfoxide / 8 h / 80 °C

2: sodium hydroxide; ethanol / 6 h / 80 °C

3: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 20 °C / Cooling with ice

With dmap; ethanol; sodium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide; In dichloromethane; dimethyl sulfoxide;