Z-Val-Leu-OMe

Base Information

Chemical Name:Z-Val-Leu-OMe
CAS No.:4817-93-0
Molecular Formula:C20H30N2O5
Molecular Weight:378.469
Hs Code.:
DSSTox Substance ID:DTXSID401194747
Nikkaji Number:J338.061K

Synonyms:Z-Val-Leu-OMe;PKLDYUWADSNDGB-IRXDYDNUSA-N;DTXSID401194747;4817-93-0;N-[(Phenylmethoxy)carbonyl]-L-valyl-L-leucine methyl ester

Suppliers and Price of Z-Val-Leu-OMe

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Z-Val-Leu-OMe

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:11
Exact Mass:378.21547206
Heavy Atom Count:27
Complexity:487

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C(=O)OC)NC(=O)C(C(C)C)NC(=O)OCC1=CC=CC=C1
Isomeric SMILES:CC(C)C[C@@H](C(=O)OC)NC(=O)[C@H](C(C)C)NC(=O)OCC1=CC=CC=C1

Technology Process of Z-Val-Leu-OMe

There total 19 articles about Z-Val-Leu-OMe which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 67-56-1
methanol

: 52616-98-5
Cbz-Val-Leu-OtBu

: 4817-93-0
(S)-methyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanamido)-4-methylpentanoate

Guidance literature:: With hydrogenchloride;
DOI:10.1016/0040-4039(91)80417-5

Reference yield: 99.0%

: 1149-26-4
(S)-N-(benzyloxycarbonyl)valine

: 7517-19-3
methyl (L)-leucinate hydrochloride

: 4817-93-0
(S)-methyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanamido)-4-methylpentanoate

Guidance literature:: With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 12h;
DOI:10.1021/acs.orglett.7b01761

Reference yield: 99.0%

: 2666-93-5
(S)-Leu-OMe

: 1149-26-4
(S)-N-(benzyloxycarbonyl)valine

: 4817-93-0
(S)-methyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanamido)-4-methylpentanoate

Guidance literature:: With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In dichloromethane;
DOI:10.1071/CH04080