1-(Difluoromethylsulfonyl)-4-methylbenzene

Base Information

Chemical Name:1-(Difluoromethylsulfonyl)-4-methylbenzene
CAS No.:4837-17-6
Molecular Formula:C8H8F2O2S
Molecular Weight:206.213
Hs Code.:
DSSTox Substance ID:DTXSID70368008
Wikidata:Q82154280

Synonyms:1-(difluoromethylsulfonyl)-4-methylbenzene;4837-17-6;Benzene, 1-[(difluoromethyl)sulfonyl]-4-methyl-;1-((difluoromethyl)sulfonyl)-4-methylbenzene;1-DIFLUOROMETHANESULFONYL-4-METHYLBENZENE;SCHEMBL9732139;DTXSID70368008;MIENFRAZJABQIZ-UHFFFAOYSA-N;HMS1787P18;difluoromethyl 4-methylphenyl sulfone;AKOS003240001;CCG-306345

Suppliers and Price of 1-(Difluoromethylsulfonyl)-4-methylbenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 1-(Difluoromethylsulfonyl)-4-methylbenzene

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:206.02130699
Heavy Atom Count:13
Complexity:248

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)C(F)F

Technology Process of 1-(Difluoromethylsulfonyl)-4-methylbenzene

There total 7 articles about 1-(Difluoromethylsulfonyl)-4-methylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1,1,1,3,3-pentafluoro-3-tosylpropane-2,2-diol

: 4837-17-6
1-((difluoromethyl)sulfonyl)-4-methylbenzene

Guidance literature:: With water; triethylamine; In tetrahydrofuran; at 20 ℃; for 0.5h;
DOI:10.1016/j.tetlet.2016.12.018

Reference yield: 82.0%

: 275818-95-6
sodium difluoromethanesulfinate

: 459-44-9
4-methylbenzenediazonium tetrafluoroborate

: 4837-17-6
1-((difluoromethyl)sulfonyl)-4-methylbenzene

Guidance literature:: sodium difluoromethanesulfinate; With copper(I) thiophene-2-carboxylate; In acetonitrile; at 20 ℃; for 0.0833333h; Inert atmosphere; Schlenk technique;

4-methylbenzenediazonium tetrafluoroborate; In acetonitrile; at 20 ℃; for 0.75h; Inert atmosphere; Schlenk technique; Sealed tube;
DOI:10.1002/cjoc.201700748