N-Methoxy-2,4-diphenyl-5-thiazolecarboxamide

Base Information

Chemical Name:N-Methoxy-2,4-diphenyl-5-thiazolecarboxamide
CAS No.:502935-48-0
Molecular Formula:C17H14N2O2S
Molecular Weight:310.376
Hs Code.:
DSSTox Substance ID:DTXSID801257743
Nikkaji Number:J1.819.284E

Synonyms:DTXSID801257743;AKOS016896849;502935-48-0;N-Methoxy-2,4-diphenyl-5-thiazolecarboxamide;Z193294508

Suppliers and Price of N-Methoxy-2,4-diphenyl-5-thiazolecarboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-Methoxy-2,4-diphenyl-5-thiazolecarboxamide

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:310.07759887
Heavy Atom Count:22
Complexity:368

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CONC(=O)C1=C(N=C(S1)C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of N-Methoxy-2,4-diphenyl-5-thiazolecarboxamide

There total 3 articles about N-Methoxy-2,4-diphenyl-5-thiazolecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 593-56-6
N-methoxylamine hydrochloride

: 857284-13-0
2,4-diphenylthiazole-5-carbonyl chloride

: 502935-48-0
2,4-diphenyl-thiazole-5-carboxylic acid methoxy-amide

Guidance literature:: With pyridine; In dichloromethane; at 0 ℃;
DOI:10.1016/S0040-4020(02)00903-1

Reference yield:

: 402567-86-6
ethyl 2,4-diphenylthiazole-5-carboxylate

: 502935-48-0
2,4-diphenyl-thiazole-5-carboxylic acid methoxy-amide

Guidance literature:: Multi-step reaction with 3 steps

1: 93 percent / sodium hydroxide / methanol; H₂O / 20 °C

2: thionyl chloride / toluene / Heating

3: pyridine / CH₂Cl₂ / 0 °C

With pyridine; sodium hydroxide; thionyl chloride; In methanol; dichloromethane; water; toluene;
DOI:10.1016/S0040-4020(02)00903-1

Reference yield:

: 502935-47-9
2,4-diphenylthiazole-5-carboxylic acid

: 502935-48-0
2,4-diphenyl-thiazole-5-carboxylic acid methoxy-amide

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / toluene / Heating

2: pyridine / CH₂Cl₂ / 0 °C

With pyridine; thionyl chloride; In dichloromethane; toluene;
DOI:10.1016/S0040-4020(02)00903-1