16-Dehydroprogesterone

Base Information Edit

Chemical Name:16-Dehydroprogesterone
CAS No.:1096-38-4
Molecular Formula:C21H28O2
Molecular Weight:312.452
Hs Code.:
European Community (EC) Number:214-142-8
NSC Number:11037,9785
UNII:JU0YQ9DZ2O
DSSTox Substance ID:DTXSID10862535
Nikkaji Number:J127.974B
Wikidata:Q27102899
Metabolomics Workbench ID:35442
Mol file:1096-38-4.mol

Synonyms:16-dehydroprogesterone;delta(16)-progesterone

Suppliers and Price of 16-Dehydroprogesterone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
16-Dehydroprogesterone
1g
$ 275.00

TRC
16-Dehydroprogesterone
250mg
$ 90.00

Sigma-Aldrich
PREGNA-4,16-DIENE-3,20-DIONE AldrichCPR
1ea
$ 115.00

ChemScene
16-?Dehydroprogesterone 99.53%
50mg
$ 50.00

Chemenu
Pregna-4,16-diene-3,20-dione 95%
5g
$ 224.00

Chemenu
Pregna-4,16-diene-3,20-dione 95%
25g
$ 729.00

Chemenu
Pregna-4,16-diene-3,20-dione 95%
10g
$ 365.00

American Custom Chemicals Corporation
4,16-PREGNADIENE-3,20-DIONE 95.00%
5G
$ 1261.26

American Custom Chemicals Corporation
4,16-PREGNADIENE-3,20-DIONE 95.00%
1G
$ 975.45

AHH
16-Dehydroprogesterone 98%
5g
$ 297.00

Total 77 raw suppliers

Chemical Property of 16-Dehydroprogesterone Edit

Chemical Property:

Vapor Pressure:1.11E-08mmHg at 25°C
Melting Point:185-187 °C(lit.)
Refractive Index:1.557
Boiling Point:460.983 °C at 760 mmHg
Flash Point:171.519 °C
PSA：34.14000
Density:1.11 g/cm³
LogP:4.64360
Storage Temp.:2-8°C
Solubility.:Chloroform (Slightly), DMSO (Slightly, Sonicated), Methanol (Slightly)
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:312.208930132
Heavy Atom Count:23
Complexity:640

Purity/Quality:

99% ^*data from raw suppliers

16-Dehydroprogesterone ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 20/21/22-40
Safety Statements: 22-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC(=O)C1=CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C
Isomeric SMILES:CC(=O)C1=CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C
Uses 16-Dehydroprogesterone is used in the direct organocatalytic stereoselective transfer hydrogenation of conjugated olefins of steroids. 16-Dehydroprogesterone is a form of Progesterone (P755900), a steroid hormone produced by the corpus luteum that induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.

Technology Process of 16-Dehydroprogesterone

There total 80 articles about 16-Dehydroprogesterone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 104010-41-5
16-dehydropregnenolone

: 1096-38-4
16-dehydroprogesterone

Guidance literature:: With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen; ferric nitrate; In dichloromethane; at 22 - 30 ℃; for 16h; Reagent/catalyst; Temperature; Large scale;

Reference yield: 97.0%

: 434-03-7
levonorgestrel

: 1096-38-4
16-dehydroprogesterone

Guidance literature:: With trifluoroacetic acid; [Ru(η³-2-C3H4Me)(CO)(1,1'-(Ph2P)2-ferrocene)][SbF6]; In tetrahydrofuran; for 26h; Heating;
DOI:10.1002/adsc.200505294