17alpha-Hydroxyprogeoterone

Base Information Edit

Chemical Name:17alpha-Hydroxyprogeoterone
CAS No.:68-96-2
Molecular Formula:C21H20O3
Molecular Weight:330.467
Hs Code.:38220090
European Community (EC) Number:210-062-2
NSC Number:759566
ChEMBL ID:CHEMBL302529
Mol file:68-96-2.mol

Synonyms:17alpha-Hydroxyprogeoterone;(10R,13S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one;Spectrum_000380;Spectrum2_001219;Spectrum3_001758;Spectrum4_001785;Spectrum5_000429;BSPBio_003496;KBioGR_002331;KBioSS_000860;SPECTRUM1701060;SPBio_001038;CHEMBL302529;MEGxm0_000478;SCHEMBL13558389;ACon1_001962;KBio2_000860;KBio2_003428;KBio2_005996;KBio3_002716;HMS3264O19;HMS3371H06;Pharmakon1600-01701060;604-09-1;CCG-39157;NSC759566;AKOS002598473;Hydroxyprogesterone Caproate impurity A;NSC-759566;NCGC00178033-01;NCGC00178033-02;SBI-0207050.P001;AB01563381_01;BRD-A39791822-001-02-8;BRD-A39791822-001-03-6;BRD-A39791822-001-04-4;17-Hydroxyprogesterone;17-Hydroxypregn-4-ene-3,20-dione;17?-Hydroxy-P4;17?-Hydroxylutin

Suppliers and Price of 17alpha-Hydroxyprogeoterone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
17α-HydroxyProgesterone
50g
$ 400.00

TCI Chemical
17alpha-Hydroxyprogesterone >98.0%(HPLC)
25g
$ 225.00

TCI Chemical
17alpha-Hydroxyprogesterone >98.0%(HPLC)
5g
$ 76.00

Sigma-Aldrich
17α-Hydroxyprogesterone solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
1 mL
$ 106.00

Sigma-Aldrich
17α-Hydroxyprogesterone solution 1.0mg/mL in methanol, ampule of 1mL, certified reference material
085-1ml
$ 103.00

Sigma-Aldrich
17α-Hydroxyprogesterone VETRANAL , analytical standard
50mg
$ 90.80

Sigma-Aldrich
17α-Hydroxyprogesterone VETRANAL , analytical standard
10mg
$ 58.80

Sigma-Aldrich
17α-Hydroxyprogesterone ≥95%
5g
$ 79.80

Sigma-Aldrich
17α-Hydroxyprogesterone ≥95%
25g
$ 320.00

Medical Isotopes, Inc.
17α-Hydroxyprogesterone
5 g
$ 190.00

Total 182 raw suppliers

Chemical Property of 17alpha-Hydroxyprogeoterone Edit

Chemical Property:

Appearance/Colour:White solid
Vapor Pressure:2.37E-11mmHg at 25°C
Melting Point:276 °C
Refractive Index:90 ° (C=1, CHCl3)
Boiling Point:482.9 °C at 760 mmHg
PKA:13.03±0.60(Predicted)
Flash Point:259.9 °C
PSA：54.37000
Density:1.15 g/cm³
LogP:3.69430
Storage Temp.:-20?C Freezer
Solubility.:soluble in Chloroform
Water Solubility.:5.056mg/L(20 oC)
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:330.21949481
Heavy Atom Count:24
Complexity:635

Purity/Quality:

99.00% ^*data from raw suppliers

17α-HydroxyProgesterone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T,F
Statements: 61-39/23/24/25-23/24/25-11
Safety Statements: 53-22-36/37/39-45-36/37-16

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1(CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)O
Isomeric SMILES:CC(=O)[C@]1(CCC2[C@@]1(CCC3C2CCC4=CC(=O)CC[C@]34C)C)O
Uses Progesteron. It was isolated from adrenal glands. anticoagulant 17α-Hydroxy Progesterone is a metabolite of Progesterone. It was isolated from adrenal glands.
Indications Hydroxyprogesterone has been used prophylactically for the 12th to 37th week of pregnancy, particularly in women who are in the high-risk category for premature delivery (e.g., those with a history of premature delivery or spontaneous abortion). A concern relating to teratogenic potential has limited its use. Hydroxyprogesterone as a tocolytic agent requires further evaluation before its routine prophylactic administration can be recommended.
Therapeutic Function Progestin

Technology Process of 17alpha-Hydroxyprogeoterone

There total 91 articles about 17alpha-Hydroxyprogeoterone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%