Chlorobis(2,4,6-trimethylphenyl)silane

Base Information

• Chemical Name: Chlorobis(2,4,6-trimethylphenyl)silane
• CAS No.: 50490-74-9
• Molecular Formula: C18H23ClSi
• Molecular Weight: 302.919
• DSSTox Substance ID: DTXSID00851337
• Mol file: 50490-74-9.mol

Synonyms:chlorodimesitylsilane;Chlorobis(2,4,6-trimethylphenyl)silane;50490-74-9;DTXSID00851337

Chemical Property of Chlorobis(2,4,6-trimethylphenyl)silane

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 301.1179299
• Heavy Atom Count: 20
• Complexity: 265

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC(=C(C(=C1)C)[Si](C2=C(C=C(C=C2C)C)C)Cl)C

Technology Process of Chlorobis(2,4,6-trimethylphenyl)silane

There total 6 articles about Chlorobis(2,4,6-trimethylphenyl)silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

2,4,6-trimethylphenyl lithium-diethylether 1/1 → chloro-di-(2,4,6-trimethylphenyl)silane (50490-74-9)

Guidance literature:

With trichlorosilane; In benzene;

DOI:10.1016/0022-328X(88)89074-0

Reference yield: 55.0%

mesityllithium (5806-59-7) → chloro-di-(2,4,6-trimethylphenyl)silane (50490-74-9)

Guidance literature:

With trichlorosilane; In toluene; 1.) from -70 deg C to RT, 2.) 100 deg C, 8 h;

DOI:10.1016/S0022-328X(00)90001-9

Reference yield:

2,4,6-trimethylphenyl bromide (576-83-0) → chloro-di-(2,4,6-trimethylphenyl)silane (50490-74-9)

Guidance literature:

With trichlorosilane; magnesium; Multistep reaction; 1.) THF, 2.) ether, THF, 0 deg C; reflux, 1 h 30 min;

DOI:10.1016/0022-328X(95)06036-V

upstream raw materials:

2,4,6-trimethylphenyl bromide

mesityllithium

2-mesitylmagnesium bromide

Downstream raw materials:

1,1-Di-tert-butyl-2,2-dimesityldisilan

1,1-Dimesityl-2,2-bis-(2,4,6-triisopropylphenyl)disilan

dimesitylsilyllithium

1,1,2,2-tetramesityldisilane