4-tert-Butyl-2-(trimethylsilyl)phenol

Base Information

Chemical Name:4-tert-Butyl-2-(trimethylsilyl)phenol
CAS No.:50738-39-1
Molecular Formula:C13H22OSi
Molecular Weight:222.403
Hs Code.:
DSSTox Substance ID:DTXSID60504397
Wikidata:Q82358869
Mol file:50738-39-1.mol

Synonyms:4-tert-Butyl-2-(trimethylsilyl)phenol;50738-39-1;2-trimethylsilyl-4-t-butylphenol;DTXSID60504397

Suppliers and Price of 4-tert-Butyl-2-(trimethylsilyl)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-tert-Butyl-2-(trimethylsilyl)phenol

Chemical Property:

Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:222.143991855
Heavy Atom Count:15
Complexity:212

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1=CC(=C(C=C1)O)[Si](C)(C)C

Technology Process of 4-tert-Butyl-2-(trimethylsilyl)phenol

There total 4 articles about 4-tert-Butyl-2-(trimethylsilyl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2198-66-5
2-bromo-4-tert-butylphenol

: 4039-32-1
lithium hexamethyldisilazane

: 50738-39-1
2-hydroxy-5-tert-butylphenyltrimethylsilane

Guidance literature:: In tetrahydrofuran; at 70 ℃; for 2h;
DOI:10.1016/j.tetlet.2019.04.033

Reference yield:

: 55454-59-6
(2-Bromo-4-tert-butyl-phenoxy)-trimethyl-silane

: 50738-39-1
2-hydroxy-5-tert-butylphenyltrimethylsilane

Guidance literature:: With n-butyllithium;
DOI:10.1007/BF00926322

Reference yield:

: 98-54-4
para-tert-butylphenol

: 50738-39-1
2-hydroxy-5-tert-butylphenyltrimethylsilane

Guidance literature:: Multi-step reaction with 2 steps

1: bromine; acetic acid / 0.5 h / 0 °C

2: tetrahydrofuran / 2 h / 70 °C

With bromine; acetic acid; In tetrahydrofuran;
DOI:10.1016/j.tetlet.2019.04.033