2-bromo-6-(N-acetylcystein-S-yl)hydroquinone

Base Information

• Chemical Name: 2-bromo-6-(N-acetylcystein-S-yl)hydroquinone
• CAS No.: 126190-18-9
• Molecular Formula: C₁₁H₁₂BrNO₅S
• Molecular Weight: 350.19
• Mol file: 126190-18-9.mol

Synonyms:2-Bromo-6-(N-acetyl-L-cystein-S-yl)hydroquinone

Chemical Property of 2-bromo-6-(N-acetylcystein-S-yl)hydroquinone

Chemical Property:

• Vapor Pressure: 1.35E-14mmHg at 25°C
• Boiling Point: 586.4°Cat760mmHg
• Flash Point: 308.5°C
• PSA: 135.65000
• Density: 1.81g/cm³
• LogP: 2.38200

Purity/Quality:

2-BROMO-6-(N-ACETYLCYSTEIN-S-YL)HYDROQUINONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-bromo-6-(N-acetylcystein-S-yl)hydroquinone

There total 2 articles about 2-bromo-6-(N-acetylcystein-S-yl)hydroquinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromobenzene-1,4-diol (583-69-7) → S-(3-Bromo-2,5-dihydroxyphenyl)mercapturic acid (126190-18-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 87 percent / NaClO₃, 2percent H₂SO₄ / V₂O₅

2: methanol / 2 h

With sodium chlorate; sulfuric acid; vanadia; In methanol;

DOI:10.1021/jo00296a034

Reference yield:

N-acetylcystein (616-91-1,7696-05-1) + 2-bromo-1,4-benzoquinone (3958-82-5) → (R)-2-Acetylamino-3-(4-bromo-2,5-dihydroxy-phenylsulfanyl)-propionic acid (126216-13-5) + (R)-2-Acetylamino-3-(2-bromo-3,6-dihydroxy-phenylsulfanyl)-propionic acid (126190-04-3) + S-(3-Bromo-2,5-dihydroxyphenyl)mercapturic acid (126190-18-9)

Guidance literature:

In methanol; for 2h;

DOI:10.1021/jo00296a034

Reference yield:

methanol (67-56-1) + S-(3-Bromo-2,5-dihydroxyphenyl)mercapturic acid (126190-18-9) → Methyl S-(3-bromo-2,5-dihydroxyphenyl)mercapturate (126190-06-5)

Guidance literature:

With trifluoroacetic acid;

DOI:10.1021/jo00296a034

upstream raw materials:

N-acetylcystein

2-bromo-1,4-benzoquinone

2-bromobenzene-1,4-diol

Downstream raw materials:

Methyl S-(3-bromo-2,5-dihydroxyphenyl)mercapturate