3-(4-Nitrophenyl)-4,5-dihydro-1,2-oxazole-5-carboxylic acid

Base Information

Chemical Name:3-(4-Nitrophenyl)-4,5-dihydro-1,2-oxazole-5-carboxylic acid
CAS No.:508182-18-1
Molecular Formula:C10H8N2O5
Molecular Weight:236.18100
Hs Code.:
DSSTox Substance ID:DTXSID40600861
Nikkaji Number:J2.685.688D
Mol file:508182-18-1.mol

Synonyms:508182-18-1;3-(4-Nitrophenyl)-4,5-dihydro-1,2-oxazole-5-carboxylic acid;SCHEMBL10387942;DTXSID40600861;MFCD11203724;3-(4-Nitrophenyl)-4,5-dihydroisoxazole-5-carboxylic acid

Suppliers and Price of 3-(4-Nitrophenyl)-4,5-dihydro-1,2-oxazole-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 3-(4-Nitrophenyl)-4,5-dihydro-1,2-oxazole-5-carboxylic acid

Chemical Property:

PSA：104.71000
LogP:1.13120
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:236.04332136
Heavy Atom Count:17
Complexity:354

Purity/Quality:: NLT 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(ON=C1C2=CC=C(C=C2)[N+](=O)[O-])C(=O)O

Technology Process of 3-(4-Nitrophenyl)-4,5-dihydro-1,2-oxazole-5-carboxylic acid

There total 2 articles about 3-(4-Nitrophenyl)-4,5-dihydro-1,2-oxazole-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

: 79-10-7
acrylic acid

: 1129-37-9,174848-02-3,20707-69-1
4-nitrobenzaldehyde oxime

: 508182-18-1
3-(4-nitrophenyl)-4,5-dihydroisoxazole-5-carboxylic acid

Guidance literature:: With pyridine; N-chloro-succinimide; In chloroform; at 20 ℃; for 4h; regioselective reaction; Inert atmosphere;
DOI:10.1002/ejoc.200801026