Furan, 2-ethyltetrahydro-

Base Information

• Chemical Name: Furan, 2-ethyltetrahydro-
• CAS No.: 1003-30-1
• Deprecated CAS: 123931-62-4
• Molecular Formula: C6H12O
• Molecular Weight: 100.161
• DSSTox Substance ID: DTXSID00870826
• Nikkaji Number: J260.978I
• Mol file: 1003-30-1.mol

Synonyms:2-ethyltetrahydrofuran;Furan, 2-ethyltetrahydro-;2-ethyloxolane;1003-30-1;123931-62-4;SCHEMBL170737;DTXSID00870826

Chemical Property of Furan, 2-ethyltetrahydro-

Chemical Property:

• Melting Point: -114°C (estimate)
• Refractive Index: 1.4170
• Boiling Point: 109°Cat760mmHg
• Flash Point: 14°C
• PSA: 9.23000
• Density: 0.853g/cm³
• LogP: 1.57540
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 100.088815002
• Heavy Atom Count: 7
• Complexity: 52.1

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1CCCO1

Technology Process of Furan, 2-ethyltetrahydro-

There total 43 articles about Furan, 2-ethyltetrahydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

n-hexyl-hypochlorite (82004-64-6) → 2-ethyltetrahydrofuran (1003-30-1,123931-62-4) + 4-chloro-1-hexanol (58705-86-5) + hexanal (66-25-1) + hexan-1-ol (111-27-3)

Guidance literature:

With sodium hydrogencarbonate; iron(II) sulfate; In tetrachloromethane; Ambient temperature; protected from the light;

DOI:10.1016/0040-4020(81)85021-1

Reference yield: 56.0%

hexan-1-ol (111-27-3) → 2-ethyltetrahydrofuran (1003-30-1,123931-62-4) + 5-chloro-1-hexanol (85696-65-7) + 4-chloro-1-hexanol (58705-86-5) + hexanal (66-25-1)

Guidance literature:

With lead(IV) acetate; lithium chloride; In benzene; at 80 ℃; Product distribution; various alcohols, other metal halogenides;

DOI:10.1007/BF00953706

Reference yield: 47.0%

tetrahydrofuran (109-99-9,24979-97-3,77392-70-2) + ethylmagnesium chloride (2386-64-3) → 2-ethyltetrahydrofuran (1003-30-1,123931-62-4)

Guidance literature:

With C₃₁H₃₈ClN₃NiO₂^(1-)*Li⁽¹⁺⁾; In ethylene dibromide; at 25 ℃; for 2h; Catalytic behavior; Inert atmosphere;

DOI:10.1007/s10562-013-1170-8

upstream raw materials:

3-(tetrahydrofuran-2-yl)propan-1-ol

(furan-2-yl)ethylene

2-ethylfuran

hexane-1,4-diol

Downstream raw materials:

1,4-diboromohexane

hexa-2,4-diene

1,4-hexadiene

hexa-1,3-diene

Refernces

• 1、 Zhu, Xuehua,Li, Guoyao,Xu, Fan,Zhang, Yong,Xue, Mingqiang,Shen, Qi. "Investigation and mechanistic study into intramolecular hydroalkoxylation of unactivated alkenols catalyzed by cationic lanthanide complexes". . p. 1451 - 1458. Retrieved 2017.
• 2、 Dauzonne,D. et al.. "-". . p. 19 - 25. Retrieved 1977.
• 3、 Mihailovic et al.. "-". . p. 981. Retrieved 1969.
• 4、 Ye, Tian-Nan,Li, Jiang,Kitano, Masaaki,Hosono, Hideo. "Unique nanocages of 12CaO·7Al2O3 boost heterolytic hydrogen activation and selective hydrogenation of heteroarenes over ruthenium catalyst". . p. 749 - 756. Retrieved 2017/05/22.