2-Pyrrolidinone, 1-((4-methoxyphenyl)methyl)-

Base Information

Chemical Name:2-Pyrrolidinone, 1-((4-methoxyphenyl)methyl)-
CAS No.:60737-65-7
Molecular Formula:C12H15NO2
Molecular Weight:205.257
Hs Code.:2933998090
DSSTox Substance ID:DTXSID60209557
Nikkaji Number:J3.409.455A
Wikidata:Q83083889
Mol file:60737-65-7.mol

Synonyms:60737-65-7;1-[(4-methoxyphenyl)methyl]pyrrolidin-2-one;1-(4-Methoxy-benzyl)-pyrrolidin-2-one;2-Pyrrolidinone, 1-((4-methoxyphenyl)methyl)-;1-(p-Methoxybenzyl)-2-pyrrolidinone;1-((4-Methoxyphenyl)methyl)-2-pyrrolidinone;1-(4-methoxybenzyl)pyrrolidin-2-one;MFCD01960843;SCHEMBL4509396;DTXSID60209557;JFXXBYZUNOVBOQ-UHFFFAOYSA-N;1-(p-Methoxybenzyl)pyrrolidine-2-one;AKOS016384544;1-(4-Methoxybenzyl)-pyrrolidin-2-one;NS-02182;LS-138880;CS-0322823

Suppliers and Price of 2-Pyrrolidinone, 1-((4-methoxyphenyl)methyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-[(4-methoxyphenyl)methyl]pyrrolidin-2-one
25mg
$ 175.00

TRC
1-[(4-methoxyphenyl)methyl]pyrrolidin-2-one
2.5mg
$ 45.00

Matrix Scientific
1-(4-Methoxybenzyl)-pyrrolidin-2-one 95%+
1g
$ 818.00

Matrix Scientific
1-(4-Methoxybenzyl)-pyrrolidin-2-one 95%+
500mg
$ 490.00

Advanced Chemicals Intermediatesced Chemicals Intermediates
1-(4-Methoxy-benzyl)-pyrrolidin-2-one 95%+
500mg
$ 239.25

Acints
1-(4-Methoxy-benzyl)-pyrrolidin-2-one 95%+
5g
$ 1152.75

Acints
1-(4-Methoxy-benzyl)-pyrrolidin-2-one 95%+
1g
$ 398.75

Acints
1-(4-Methoxy-benzyl)-pyrrolidin-2-one 95%+
500mg
$ 239.25

Total 4 raw suppliers

Chemical Property of 2-Pyrrolidinone, 1-((4-methoxyphenyl)methyl)-

Chemical Property:

Vapor Pressure:4.32E-06mmHg at 25°C
Boiling Point:383.7°C at 760 mmHg
Flash Point:185.8°C
PSA：29.54000
Density:1.149g/cm³
LogP:1.75550
XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:205.110278721
Heavy Atom Count:15
Complexity:222

Purity/Quality:

99% ^*data from raw suppliers

1-[(4-methoxyphenyl)methyl]pyrrolidin-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)CN2CCCC2=O
Uses 1-[(4-Methoxyphenyl)methyl]pyrrolidin-2-one is a pyrrolidine derivatives with pharmaceutical application.

Technology Process of 2-Pyrrolidinone, 1-((4-methoxyphenyl)methyl)-

There total 15 articles about 2-Pyrrolidinone, 1-((4-methoxyphenyl)methyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 616-45-5
2-pyrrolidinon

: 824-94-2
p-methoxybenzyl chloride

: 60737-65-7
1-(p-methoxybenzyl)-2-pyrrolidinone

Guidance literature:: With sodium hydride; tetrabutyl phosphonium bromide; In tetrahydrofuran; at 25 ℃; for 24h;
DOI:10.3987/com-06-s(w)38

Reference yield: 92.0%

: 616-45-5
2-pyrrolidinon

: 2746-25-0
p-Methoxybenzyl bromide

: 60737-65-7
1-(p-methoxybenzyl)-2-pyrrolidinone

Guidance literature:: 2-pyrrolidinon; With sodium hydride; In tetrahydrofuran; paraffin oil; at 0 ℃; for 0.5h; Inert atmosphere;

p-Methoxybenzyl bromide; In tetrahydrofuran; paraffin oil; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1002/adsc.201000189

Reference yield: 88.0%

: 1-(4-methoxybenzyl)-3-[(2,2,6,6-tetramethylpiperidin-1-yl)oxy]piperidin-2-one

: 60737-65-7
1-(p-methoxybenzyl)-2-pyrrolidinone

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In diethyl ether; at 0 ℃; for 0.25h; Reagent/catalyst; Solvent; Inert atmosphere;
DOI:10.1002/anie.201903880