N-[2-(4-Methoxyphenoxy)-4-nitrophenyl]methanesulfonamide

Base Information

Chemical Name:N-[2-(4-Methoxyphenoxy)-4-nitrophenyl]methanesulfonamide
CAS No.:51765-76-5
Molecular Formula:C14H14N2O6S
Molecular Weight:338.341
Hs Code.:
European Community (EC) Number:669-262-7
DSSTox Substance ID:DTXSID40432386
Nikkaji Number:J3.440.033D
Wikidata:Q82246453
ChEMBL ID:CHEMBL3628727
Mol file:51765-76-5.mol

Synonyms:51765-76-5;2'-(4-Methoxyphenoxy)-4'-nitromethanesulfonanilide;N-[2-(4-Methoxyphenoxy)-4-nitrophenyl]methanesulfonamide;CHEMBL3628727;Methanesulfonamide, N-[2-(4-methoxyphenoxy)-4-nitrophenyl]-;DTXSID40432386;BDBM50128688;AKOS024328456;4-nitro-2-(4'-methoxy-phenoxy)-methanesulfonyl aniline;4-nitro-2-[(4'-methoxy)-phenoxy]-methanesulfonyl aniline

Suppliers and Price of N-[2-(4-Methoxyphenoxy)-4-nitrophenyl]methanesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-[2-(4-Methoxyphenoxy)-4-nitrophenyl]methanesulfonamide

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:338.05725734
Heavy Atom Count:23
Complexity:492

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)OC2=C(C=CC(=C2)[N+](=O)[O-])NS(=O)(=O)C

Technology Process of N-[2-(4-Methoxyphenoxy)-4-nitrophenyl]methanesulfonamide

There total 9 articles about N-[2-(4-Methoxyphenoxy)-4-nitrophenyl]methanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.3%

: 721448-65-3
N-(2-(4-methoxyphenoxy)phenyl)methanesulfonamide

: 51765-76-5
N-(2-(4-methoxyphenoxy)-4-nitrophenyl)methanesulfonamide

Guidance literature:: With nitric acid; acetic anhydride; acetic acid; at 85 - 90 ℃;

Reference yield: 66.6%

: 2-(4-methoxyphenoxy)-4-nitroaniline

: 124-63-0
methanesulfonyl chloride

: 51765-76-5
N-(2-(4-methoxyphenoxy)-4-nitrophenyl)methanesulfonamide

Guidance literature:: 2-(4-methoxyphenoxy)-4-nitroaniline; methanesulfonyl chloride; With triethylamine; In dichloromethane; at 20 ℃; for 23h; Cooling with ice;

With sodium hydroxide; In water; for 16h; Reflux;
DOI:10.1016/j.bmc.2015.10.007

Reference yield:

: 58656-16-9
2-(4-methoxyphenoxy)nitrobenzene

: 51765-76-5
N-(2-(4-methoxyphenoxy)-4-nitrophenyl)methanesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: 75 percent / iron; HCl / H₂O / 1 h / 80 °C

2: 85 percent / Et₃N / CH₂Cl₂ / 0 °C

3: HNO₃ / acetic acid / 60 °C

With hydrogenchloride; nitric acid; iron; triethylamine; In dichloromethane; water; acetic acid;