4-(tert-Butyl)phthalamide

Base Information

Chemical Name:4-(tert-Butyl)phthalamide
CAS No.:52319-96-7
Molecular Formula:C12H16N2O2
Molecular Weight:220.271
Hs Code.:
DSSTox Substance ID:DTXSID20600667
Wikidata:Q82496859
Mol file:52319-96-7.mol

Synonyms:4-(tert-Butyl)phthalamide;52319-96-7;4-tert-Butylbenzene-1,2-dicarboxamide;1,2-Benzenedicarboxamide, 4-(1,1-dimethylethyl)-;4-t-butylphthalamide;SCHEMBL10418922;DTXSID20600667;DQFQNSBLKACADK-UHFFFAOYSA-N;SB80002;A901427

Suppliers and Price of 4-(tert-Butyl)phthalamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 4-(tert-Butyl)phthalamide

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:220.121177757
Heavy Atom Count:16
Complexity:294

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1=CC(=C(C=C1)C(=O)N)C(=O)N

Technology Process of 4-(tert-Butyl)phthalamide

There total 6 articles about 4-(tert-Butyl)phthalamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 4-tert-butylphthaloyl chloride

: 52319-96-7
4-tert-Butylphthalsaeurediamid

Guidance literature:: With ammonia; In 1,4-dioxane; at -3 - 20 ℃; Temperature;

Reference yield: 79.7%

: 50727-07-6
4-tert-butylphthalimide

: 52319-96-7
4-tert-Butylphthalsaeurediamid

Guidance literature:: With ammonium hydroxide; for 3h;

Reference yield:

: 95-47-6
o-xylene

: 52319-96-7
4-tert-Butylphthalsaeurediamid

Guidance literature:: Multi-step reaction with 4 steps

1: iodine / 50 °C

2: acetic acid; potassium permanganate / tert-butyl alcohol; water / Reflux

3: thionyl chloride / Reflux

4: ammonia / 1,4-dioxane / -3 - 20 °C

With potassium permanganate; thionyl chloride; ammonia; iodine; acetic acid; In 1,4-dioxane; water; tert-butyl alcohol;