4,7-dichloro-2,3-dihydro-1H-inden-1-one

Base Information

• Chemical Name: 4,7-dichloro-2,3-dihydro-1H-inden-1-one
• CAS No.: 52977-63-6
• Molecular Formula: C9H6Cl2O
• Molecular Weight: 201.04900
• European Community (EC) Number: 958-914-9
• Mol file: 52977-63-6.mol

Synonyms:4,7-dichloro-2,3-dihydro-1H-inden-1-one;52977-63-6;4,7-Dichloro-1-indanone;4,7-dichloro-2,3-dihydroinden-1-one;C9H6Cl2O;WLZ3236;AMY27958;CCA97763;MFCD16876799;AKOS026739280;DS-19447;CS-0030410;F52751

Chemical Property of 4,7-dichloro-2,3-dihydro-1H-inden-1-one

Chemical Property:

• Melting Point: 111 °C
• PSA: 17.07000
• LogP: 3.12230
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 199.9795702
• Heavy Atom Count: 12
• Complexity: 205

Purity/Quality:

99.99%HPLC ^*data from raw suppliers

4,7-Dichloro-2,3-dihydro-1H-inden-1-one 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CC(=O)C2=C(C=CC(=C21)Cl)Cl

Technology Process of 4,7-dichloro-2,3-dihydro-1H-inden-1-one

There total 7 articles about 4,7-dichloro-2,3-dihydro-1H-inden-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-dichloroiodobenzene (29682-41-5) → 4,7-dichloro-2,3-dihydro-1H-inden-1-one (52977-63-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 94 percent / Et₃N; Pd(OAc)2 / acetonitrile / 1 h / 110 °C

2: 95 percent / H₂ / PtO₂ / ethyl acetate / 24 h / 20 °C

3: SOCl₂ / 4 h / Heating

4: 1.001 g / AlCl₃ / CS₂ / 24 h / Heating

With palladium diacetate; aluminium trichloride; thionyl chloride; hydrogen; triethylamine; platinum(IV) oxide; In carbon disulfide; ethyl acetate; acetonitrile; 1: Heck coupling / 4: Friedel-Crafts acylation;

DOI:10.1016/S0968-0896(03)00059-2

Reference yield:

3-(2,5-dichlorophenyl)acrylic acid (20595-47-5) → 4,7-dichloro-2,3-dihydro-1H-inden-1-one (52977-63-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 95 percent / H₂ / PtO₂ / ethyl acetate / 24 h / 20 °C

2: SOCl₂ / 4 h / Heating

3: 1.001 g / AlCl₃ / CS₂ / 24 h / Heating

With aluminium trichloride; thionyl chloride; hydrogen; platinum(IV) oxide; In carbon disulfide; ethyl acetate; 3: Friedel-Crafts acylation;

DOI:10.1016/S0968-0896(03)00059-2

Reference yield:

3-(2,5-dichloro-phenyl)-propionyl chloride → 4,7-dichloro-2,3-dihydro-1H-inden-1-one (52977-63-6)

Guidance literature:

With aluminium trichloride; In carbon disulfide; for 24h; Heating;

DOI:10.1016/S0968-0896(03)00059-2

upstream raw materials:

2,4,7-trichloro-indenone

carbon disulfide

aluminium trichloride

2,5-dichloroiodobenzene

Downstream raw materials:

(-)-8-(5,8-Dichloro-1,2,3,4-tetrahydro-2-naphthyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 52977-63-6 4,7-Dichloro-1-indanone

Send

Send

Metric Ton KG G Pound L ML

Send

Send