1-(2-ALLYL-PHENOXY)-3-AMINO-PROPAN-2-OL

Base Information

• Chemical Name: 1-(2-ALLYL-PHENOXY)-3-AMINO-PROPAN-2-OL
• CAS No.: 32352-07-1
• Molecular Formula: C₁₂H₁₇NO₂
• Molecular Weight: 207.272
• Mol file: 32352-07-1.mol

Synonyms:1-(o-Allylphenoxy)-2-hydroxy-3-aminopropan;1-(2-Allyl-phenoxy)-3-amino-propan-2-ol;2-hydroxy-3-(2-propenylphenoxy)propylamine;Noralprenolol;N-desisopropylalprenolol;

Chemical Property of 1-(2-ALLYL-PHENOXY)-3-AMINO-PROPAN-2-OL

Chemical Property:

• PSA: 55.48000
• LogP: 1.81380

Purity/Quality:

98%min ^*data from raw suppliers

1-(2-Allyl-phenoxy)-3-amino-propan-2-ol ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

Useful:

Technology Process of 1-(2-ALLYL-PHENOXY)-3-AMINO-PROPAN-2-OL

There total 2 articles about 1-(2-ALLYL-PHENOXY)-3-AMINO-PROPAN-2-OL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

alprenolol (13655-52-2,23846-70-0,23846-71-1,23846-72-2) → 1-(2-Allylphenoxy)-2-oxy-3-aminopropane (32352-07-1)

Guidance literature:

With rat liver microsomes alprenolol N-desisopropylase; at 37 ℃; for 0.00833333h; pH=7.4; Enzyme kinetics; Enzymatic reaction;

DOI:10.1248/bpb.18.1060

Reference yield:

→ 1-(2-Allylphenoxy)-2-oxy-3-aminopropane (32352-07-1)

Guidance literature:

2,3-Epoxid III, NH3;

Reference yield: 52.0%

1-(2-Allylphenoxy)-2-oxy-3-aminopropane (32352-07-1) + benzoyl chloride (98-88-4) → N-[3-(2-Allyl-phenoxy)-2-hydroxy-propyl]-benzamide (112169-45-6)

Guidance literature:

With triethylamine; In benzene; Ambient temperature;

DOI:10.1007/BF01146187

upstream raw materials:

alprenolol

Downstream raw materials:

N-[3-(2-Allyl-phenoxy)-2-hydroxy-propyl]-benzamide

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