Nsc66811

Base Information

Chemical Name:Nsc66811
CAS No.:6964-62-1
Molecular Formula:C23H20 N2 O
Molecular Weight:340.425
Hs Code.:
Mol file:6964-62-1.mol

Synonyms:8-Quinolinol,7-(a-anilinobenzyl)-2-methyl-(6CI,8CI); NSC 66811

Suppliers and Price of Nsc66811

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
NSC 66811
10mg
$ 438.00

Usbiological
NSC 66811
10mg
$ 425.00

TRC
NSC66811
50mg
$ 605.00

TCI Chemical
2-Methyl-7-[phenyl(phenylamino)methyl]-8-quinolinol >98.0%(GC)
25mg
$ 77.00

TCI Chemical
2-Methyl-7-[phenyl(phenylamino)methyl]-8-quinolinol >98.0%(GC)
100mg
$ 212.00

Medical Isotopes, Inc.
NSC66811
50 mg
$ 1050.00

DC Chemicals
NSC66811 >98%
250 mg
$ 1500.00

DC Chemicals
NSC66811 >98%
100 mg
$ 800.00

CSNpharm
NSC66811
50mg
$ 359.00

CSNpharm
NSC66811
100mg
$ 593.00

Total 19 raw suppliers

Chemical Property of Nsc66811

Chemical Property:

Vapor Pressure:7.92E-12mmHg at 25°C
Melting Point:143.0 to 147.0 °C
Boiling Point:529.5°Cat760mmHg
PKA:4.42±0.50(Predicted)
Flash Point:274°C
PSA：45.15000
Density:1.235g/cm³
LogP:5.52330
Storage Temp.:Store at +4°C
Solubility.:Soluble in DMSO (up to 25 mg/ml).

Purity/Quality:

97% ^*data from raw suppliers

NSC 66811 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description NSC 66811 (6964-62-1) is a novel inhibitor of the MDM2-p53 interaction. Mimics three p53 residues involved in binding to MDM2. NSC-66811 binds to MDM2 with a Ki of 120 nM. Activates p53 in cancer cells. Cell permeable.
Uses NSC 66811 is a novel inhibitor of the murine double minute 2 (MDM2)-p53 interaction. NSC 66811 activates p53 in colon cancer cells.

Technology Process of Nsc66811

There total 1 articles about Nsc66811 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 826-81-3
2-methyl-8-quinolinol

: 100-52-7
benzaldehyde

: 62-53-3
aniline

: 6964-62-1
(2-methyl-7-[phenyl(phenylamino)methyl]-8-quinolinol)

Guidance literature:: benzaldehyde; aniline; In ethanol; at 20 ℃; for 0.0833333h;

2-methyl-8-quinolinol; With pyridine; In ethanol; at 100 ℃; for 24h;
DOI:10.1016/j.bmc.2015.11.043